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Neuroscience / Neurology (structural biology) PhD Projects, Programs & Scholarships

We have 29 Neuroscience / Neurology (structural biology) PhD Projects, Programs & Scholarships

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  PhD in Structural biology/Protein biochemistry – The role of protein amyloid fibrils in disease
  Dr V Morris
Application Deadline: 14 March 2020

Funding Type

PhD Type

The Morris lab at the University of Canterbury, New Zealand, is seeking a motivated student to carry out investigations of protein aggregation.
  Integrative structural biology of 3’UTRs
  Dr P J Lukavsky, Dr B Tichý, Prof Z Zdrahal
Application Deadline: 20 February 2020

Funding Type

PhD Type

The non-coding part of the genome vastly increased from worm to humans while the number of protein-coding genes remained constant.
  PhD in Chemical Biology -- Neuropeptide Research -- University of Vienna
  Prof M Muttenthaler
Applications accepted all year round

Funding Type

PhD Type

Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  The chemistry and biophysics of phosphoryl transfer enzymes
  Prof J Waltho, Dr A Almond
Applications accepted all year round

Funding Type

PhD Type

One of the most remarkable features of the chemistry of living organisms is the evolutionary utilisation of phosphate esters to provide biopolymers that encode genetic information, deliver temporal protein regulation, generate and distribute free energy throughout the cell, and to provide a ubiquitous handle for metabolic intermediates.
  MSc by Research Programme: Deciphering the ubiquitin codes that regulate protein degradation
  Dr Y Kulathu
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Molecular and genetic mechanisms of brain structural plasticity and neurodegeneration in the fruit-fly Drosophila.
  Dr A Hidalgo
Applications accepted all year round

Funding Type

PhD Type

The brain changes throughout life. brain plasticity enables the brain to adjust in response to experience, whereas during aging natural neurodegeneration takes over.
  Are Tau fibrils induced by phosphorylation and the interaction with 14-3-3 proteins relevant for Alzheimer disease?
  Dr J Hritz, Dr JN Nováček, Dr J Pribyl
Application Deadline: 20 February 2020

Funding Type

PhD Type

Several neurodegenerative diseases are associated with the formation of fibrous protein aggregates. The fibrillization of amyloid beta peptide into amyloid plaques and the agregation of hyperphosphorylated tau protein into neurofibrillar tangles are main neuropatological signs of Alzheimer disease.
  Structural insights into ligand binding and channel gating in ATP-gated P2X7 receptor
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr S Muench
Applications accepted all year round

Funding Type

PhD Type

P2X7 receptor, belonging to the ATP-gated ion channel P2X receptor family, exhibits distinct functional and pharmacological properties that are crucial for its role in innate immunity and inflammatory diseases and cancers (Jiang et al., 2013; Caseley et al., 2014; Roger et al., 2014; Wei et al., 2018).
  A mechanistic understanding of allosteric regulation of neuronal sodium-activated potassium channels
  Research Group: BBSRC White Rose DTP
  Dr J D Lippiat, Dr S Muench, Dr A Kalli
Applications accepted all year round

Funding Type

PhD Type

The sodium-activated potassium channel KNa1.1 (KCNT1, Slack, Slo2.2) is found in neurons and couples sodium influx to excitability.
  An integrated approach to the study of cellular interactions with amyloid
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford
Applications accepted all year round

Funding Type

PhD Type

The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
  Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
  Prof D G Fernig, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive.
  Ca2+ signalling in neurodegeneration and Alzheimer’s disease
  Research Group: School of Biology
  Prof I A Hope
Applications accepted all year round

Funding Type

PhD Type

Human variants of the ryanodine receptor, the main intracellular calcium ion channel, could be responsible for Alzheimer’s disease.
  International PhD Programme in Molecular Life Sciences

Funding Type

PhD Type

 The Vienna Biocenter (VBC) PhD Programme in Life Sciences has been running since 1993, providing students from all over the world with excellent training.
  Neurocomputational mechanisms of modularity in human motor control
  Research Group: School of Biomedical Sciences
  Dr I Delis
Applications accepted all year round

Funding Type

PhD Type

Human motor behaviour is the outcome of the combined action of an extensive neural circuit that generates and controls movement and the mechanical properties of the human body.
  TRPM2 channel mechanism of neuroinflammation and neurodegeneration in Alzheimer’s disease
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr I Wood
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease (AD) is the most common cause of dementia and also a major cause of morbidity and mortality. Currently, there is no effective therapeutics to treat or slow the disease progress.
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