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Neuroscience (alzheimer) PhD Projects, Programmes & Scholarships
We have 37 Neuroscience (alzheimer) PhD Projects, Programmes & Scholarships
We have 37 Neuroscience (alzheimer) PhD Projects, Programmes & Scholarships
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Towards restoring memory dysfunction in prodromal Alzheimer’s Disease.
Project outline. Brains contain billions of specialised cells, called neurons, which are the fundamental building blocks of every circuit in the nervous system. Read more
Determining brain glycosylation in ageing and Alzheimer’s disease
Research Group:
Pharmacology and Experimental Therapeutics
Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism. Read more
4-year PhD Studentship: The molecular mechanisms of transcranial ultrasound neuromodulation as a novel therapeutic intervention in neurological disorders
Neural activity follows repetitive, rhythmic patterns, caused by oscillations in membrane potentials or synchronised action potential firing. Read more
4-year PhD Studentship: Elucidating the inflammatory crosstalk between Coronary Artery Disease and Alzheimer's Disease
There is now substantial data demonstrating an association between high morbidity and mortality cardiovascular diseases (such as atherosclerosis and atherosclerotic aneurysms) with the onset of neurodegenerative diseases, particularly those characterised by neuroinflammation such as Alzheimer's Disease. Read more
Lysozyme encapsulated gold nanoclusters – a new therapeutic agent for Alzheimer’s disease
Alzheimer’s disease (AD) has become a major medical challenge with huge social and economic consequences due to increasing life expectancy. Read more
Investigating the link between amyloid-β oligomers, neuroinflammation and cognitive deficits in preclinical models for Alzheimer’s Disease
Currently four out of the five pharmacological treatments used for Alzheimer’s disease (AD) are acetylcholinesterase inhibitors aimed at boosting the amount of acetylcholine in the brain, with the fifth being an N-methyl-D-aspartate (NMDA) receptor antagonist. Read more
Understanding how altered GABA signalling in the brain's master clock contributes to circadian rhythm disruption in Alzheimer's disease
Our circadian clock is one of the most important timing systems in our body, ensuring that neuronal activity throughout our CNS is appropriately aligned with our homeostatic, physiological, and behavioural needs across the day. Read more
Apolipoprotein E-targeted stem cell gene therapy for people with Alzheimer’s disease
Perros Trust-supported 1 Year Full MSc R Scholarship for students of Black or Mixed Black Heritage backgrounds. Project Description. Read more
Generating a disease model for Alzheimer's Disease in non-human primates
Our lab is interested in understanding and treating a devastating neurodegenerative disorder, Alzheimer’s Disease (AD), in particular aspects relating to develop appropriate disease models for AD. Read more
4-year PhD Studentship: Non-invasive imaging of the eye to predict Alzheimer’s disease
Alzheimer’s Disease (AD) is an increasing global health burden. Several genetic, health and lifestyle factors are associated with increased AD risk and it is estimated that ~1/3 AD cases are attributable to modifiable lifestyle factors. Read more
Investigating the timing and causes of vascular dysfunction in Alzheimer’s disease
Rationale. Cerebrovascular damage accelerates and exacerbates cognitive decline and brain damage in Alzheimer's disease (AD)(1, 2). Read more
Neuroinflammation, glial cell dysfunction & neurodegenerative diseases
Neurodegenerative disorders, such as Alzheimer’s disease, are often associated with chronic neuroinflammation and glial cell dysfunction that acts to exacerbate neuronal damage and loss of synapses. Read more
The breakdown of neurovascular coupling in the diseased state specifically Epilepsy and Alzheimer’s disease
Epilepsy is the most common neurological condition in the UK, affecting 1 – 2 % of the population. Epilepsies often involve only a small area of the brain - the epileptic focus – and the abnormal activity can propagate out from there. Read more
PhD Studentship - A multi-model approach to investigate the role of early neuroinflammation in dementia with Lewy bodies
Overview. Dementia with Lewy bodies (DLB) is a common form of dementia caused by the abnormal folding and aggregation of the synaptic protein alpha-synuclein. Read more