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Neuroscience PhD Projects, Programmes & Scholarships

We have 72 Neuroscience PhD Projects, Programmes & Scholarships

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We have 72 Neuroscience PhD Projects, Programmes & Scholarships

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Managing Sleep to Enhance Mental Wellbeing in Parkinson’s Disease (Ref: RDFC22/HLS/PSY/SANTHI )

Sleep serves a functional role in cognitive wellbeing across our lifespan. It is a sensitive indicator and predictor of mental problems in healthy and pathological aging. Read more

Exploring the Molecular Mechanism of Novel Mitochondrial Neurotoxins identified through a Machine Learning Approach

Mitochondrial inhibition is an important ‘OFF-target’ mechanism of drug-induced toxicity in the clinic, contributing to drug attrition in clinical trials and drug withdrawal following approval because of severe adverse events 1. Read more

Biopsychosocial Prediction Models of Pain Management Programme (PMP) Outcomes for Chronic Pain

Project background. Chronic pain is moderately or severely disabling in an estimated 8-12% of the UK population. Those struggling to cope are often referred to multidisciplinary Pain Management Programmes (PMPs), currently considered best practice for intractable chronic pain. Read more

Investigating the sex-dependent effects of macrophage insulin resistance on non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is a spectrum of liver diseases in part driven by macrophages. Premenopausal females exhibit protection from NAFLD and macrophages express estrogen receptors which have been shown to augment and dampen innate immune signalling pathways. Read more

Investigating changes in neuronal development and connectivity in a mouse model of muscimol-induced perinatal brain injury

Disruption of normal brain development during pregnancy and in infancy can lead to life-long neurological disorders. As the brain develops, there is increasing complexity of cellular structure, connectivity and functional activity. Read more
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Task responses in the mouse somatosensory cortex during flexible behaviour

  Research Group: Neuroscience
Background. Mammals have strikingly flexible and adaptable behaviour. When facing new surroundings or a new task, they can extract the situation’s underlying structure (e.g. Read more

Methods for ultrasensitive and quantitative multimodal molecular imaging of vascular inflammation

About the project. Imaging agents enable researchers to explore animal models and investigate human pathologies non-invasively and secure crucial data to understand the onset and progression of diseases and conditions at the molecular level. . Read more

Imaging the contribution of early cerebrovascular inflammation in Alzheimer's disease

Alzheimer’s disease (AD) and other neurodegenerative diseases are associated with chronic peripheral inflammation. About 40% of the population in western countries live with insulin resistance, type 2 diabetes, arterial hypertension, and obesity-related to lifestyle habits (e.g., Western-diet, tobacco addiction). Read more
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Detailed assessment of somatic genomic copy number variants (CNVs) in multiple system atrophy (MSA)

MSA is a devastating sporadic neurodegenerative disorder with strong similarities to Parkinson’s disease (PD). Both are synucleinopathies, characterised by inclusions of α-synuclein, which in MSA occur mostly in oligodendrocytes. Read more

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