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Cell Biology / Development PhD Projects, Programs & Scholarships in Newcastle

We have 21 Cell Biology / Development PhD Projects, Programs & Scholarships in Newcastle

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Newcastle  United Kingdom

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We have 21 Cell Biology / Development PhD Projects, Programs & Scholarships in Newcastle

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A new method to dissect kinase signalling pathways in health and disease

Phosphorylation is a vital regulatory mechanism in cells. Alterations in phosphorylation signalling are major contributors to disease, and numerous clinically important drugs target kinases to treat cancer and other diseases. Read more

Investigating light-activated therapeutic compounds as antifungal agents

Fungi are important pathogens of humans, animals and plants. Fungal diseases are intrinsically difficult to treat in all hosts as there are limited classes of antifungal drugs and the development of resistance is a serious problem. Read more

Targeting the Microcephalin-1 Tumour Suppressor Protein in Cancer (REF: RDF22/HLS/APP/JOWSEY)

Microcephalin-1 (MCPH1) is a tumour suppressor protein that is down-regulated in multiple cancer types. This project will investigate whether MCPH1-deficiency in cancer can be targeted therapeutically by focusing on two cellular roles of MCPH1. Read more

Non-image-forming circuits in an in vitro model of the human retina (REF: RDF22/HLS/APP/HILGEN)

The retina is the light‐sensitive tissue that lines the back of the eyeball. It contains specialised cell types that convert the visual scenery into neuronal signals which are transferred via the optic nerve to the visual areas of the brain. Read more

MRC DiMeN Doctoral Training Partnership: Cracking the sugar code: Targeting glycan sugars to improve the diagnosis and treatment of prostate cancer

Prostate cancer is the most commonly diagnosed malignancy in men, claiming over 350,000 lives worldwide annually. Despite many new treatments, their long term success rates are poor, with only one third of men with advanced disease surviving for more than 5 years. Read more

Investigating the effects of inflamm-aging on the safety and efficacy of monoclonal antibody based therapies

Our understanding of the immune response in the elderly is still in its infancy. Now, more than ever we need to understand the basic principles of immune response as the environment alters our immune system and the particles it sees. Read more

Unravelling molecular signatures of oocyte developmental competence in cattle

This project addresses a significant global problem. Rapid human population growth coupled with a projected decrease in food production due to climate change, highlights the critical role that efficient and sustainable animal production must play in achieving food security. Read more

Nutrient transport in insect-microbe symbiosis

All animals exist in symbiosis with a complex microbiome. The most intriguing, and intimate, form of symbiosis is endosymbiosis, where one partner, the microbe, exists inside cells of the other partner, the animal host. Read more

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