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cell therapy PhD Projects, Programmes & Scholarships

We have 74 cell therapy PhD Projects, Programmes & Scholarships

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We have 74 cell therapy PhD Projects, Programmes & Scholarships

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EASTBIO A novel synthetic biology approach towards anti-bacterial cell therapy

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Project Description. With the rising threat posed by antimicrobial resistance and the slow pace at which new antibiotics are being developed, never has the need for new anti-bacterial treatment strategies been more pressing. Read more

EASTBIO: Optimisation of Allogeneic GMP Grade Mesenchymal Stromal Cells To Promote The Long Term Engraftment And Function Of Islets

This PhD proposal offers the unique opportunity of working with leading clinician scientists in the field of Type 1 diabetes and cell therapy experts at the Scottish National Blood Transfusion Service with a proven track-record of taking cell therapies to the clinic. Read more

Tissue tropism in PD-1 therapy

Programmed cell death protein 1 (PD1) is an immune checkpoint receptor expressed on immature thymocytes as well as peripheral CD4+ and CD8+ T cells, Natural Killer T (NKT) cells, B cells, monocytes and subsets of dendritic cells upon activation. Read more

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

EASTBIO: Evaluation of novel therapeutic strategies to enhance islet cell viability for Islet Cell Transplantation

  Research Group: Centre for Inflammation Research
This PhD offers the opportunity to join an exciting and motivated team researching inflammation and metabolism in the context of drug discovery, precision medicine and preventing long-term harm. Read more

Promoting cancer cell’s antigen presentation for serving as better targets for T cell immunotherapy

Commercial partner: . Oxford Vacmedix UK Ltd (OVM). , Oxford. Cytotoxic T cells (CTLs), which kill tumour cells upon recognition of antigenic peptides presented by the major histocompatibility complex (MHC) on the cell surface, are the goal of precision medicine including immunotherapies. Read more

Stochastic modelling and inference for live-cell gene expression data to unravel the mechanisms of stem cell differentiation

  Research Group: Statistical Medicine and Molecular Biology
This project will develop statistical methodology and computational algorithms to estimate model parameters using live-cell imaging data provided by the lab of our collaborator Dr Cerys Manning at the University of Manchester. Read more

BBSRC PhD Studentship in “Cryogenic electron microscopy-based understanding of viral vector heterogeneity to aide process development"

About the Project. Viral vectors can be used as oncolytic viruses, gene-based vaccines, and gene therapy vectors. However, as highlighted by the adverse reactions observed with the recent ChAdOx1 nCoV-19 vaccine and gene therapy trials, gaps remain in our understanding of these products. Read more

ABM CDT The mechanisms of portable negative pressure wound therapy on wounds

Wounds are a major unmet healthcare burden that impact on millions of patients per year. From those undergoing simple surgeries to complex ulcers of the lower limbs, a common form of therapy is the use of negative pressure wound therapy. Read more

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