Synthesis of new DNA binding compounds to target genetic diseases such as cancer and diabetes. It is often assumed that DNA exists only as the iconic Watson-Crick double helix but it can actually adopt many different types of structure depending on the sequence and environmental conditions.
There is much research into trying to regain control of cell proliferation or cell death (apoptosis) in cancer. Different strategies exist to do this and a multitude of individual receptor targets are being identified in tumour cell lines and primary cells.
Research in the Marín group focuses on the application of nanoscience to address biological challenges. The main interests are in the synthesis and the use of nanomaterials as intracellular sensors and as drug delivery systems for cancer treatment.