Clostridiodes difficile is a cause of neonatal enteritis in livestock such as pigs, cattle and horses. Affected animals develop respiratory problems, abdominal distention and bloody diarrhoea leading to weight loss and in extreme cases mortality. Read more
Metastasis is the major cause of mortality in human cancers, yet we know relatively little of the fundamental biology that underlies the important transition to invasive malignancy. Read more
Centromeres are the DNA sequences on eukaryotic chromosomes that mediate accurate chromosome segregation at both mitotic and meiotic cell divisions. Read more
Typical studies of the human microbiome identify dysbiosis by sampling from healthy individuals, comparing them to individuals with a particular disease state, and reporting changes in the presence and/or abundance of bacterial species. Read more
This project aims to use high throughput sequencing technologies and molecular approaches to understand how RNA epitranscriptomic processes contribute to susceptibility to human disorders of the brain. Read more
We are seeking a highly motivated candidate with strong academic background in immunology, chemistry, biology or related area for a multidisciplinary PhD project focused on development of biomaterials with immune modulatory properties with potential applications in immune therapy and vaccination. Read more
When a virus infects a host, the innate immune response is activated to control the infection. Therefore, all pathogenic viruses have evolved ways to counteract that response to ensure their replication and transmission to a new host. Read more
Endothelial cell proliferation and lymphatic cell proliferation known as angiogenesis and lymphangiogenesis respectively are both regulated by ligands in the VEGF signalling pathway. In general endothelial and lymphatic cells in healthy individuals are quiescent and do not proliferate. Read more
Project ID. S3 8. As we listen to the world around us, we automatically learn the structure of the sounds we hear and form predictions about what we will hear next. Read more
Project ID. S3 1. Around 50%-60% of individuals in the UK report playing sport on a weekly basis. Two million people in England alone play football at least twice a month. Read more
Project ID. SST9. This project hypothesises that the genetic reprogramming of human mesenchymal stromal cells will lead to enhanced tissue regeneration through the increased production of growth factors, potentially aiding the development of personalised cell therapies. Read more
Sweet snacks and dessert tend to give consumers a great pleasure and satisfaction, but often it also gives consumers a guilty emotion after consumption due to its high calorie content. Read more
Each year millions of tonnes of waste electrical and electronic equipment (WEEE) are generated in the EU, but only 30% is reported as properly collected and recycled, while the majority ends up in landfill. Read more
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