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Biological Sciences PhD Projects, Programmes & Scholarships in Nottingham

We have 33 Biological Sciences PhD Projects, Programmes & Scholarships in Nottingham

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Biological Sciences

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Nottingham  United Kingdom

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We have 33 Biological Sciences PhD Projects, Programmes & Scholarships in Nottingham

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Identification and characterisation of bacteriocins from environmental samples active against strains of Clostridium difficile.

Clostridiodes difficile is a cause of neonatal enteritis in livestock such as pigs, cattle and horses. Affected animals develop respiratory problems, abdominal distention and bloody diarrhoea leading to weight loss and in extreme cases mortality. Read more

Characterising congenital heart disease variants in Drosophila

Congenital heart disease (CHD) is the most common congenital defect affecting approximately 1% of live births contributing to a significance incidence of birth-defect related mortality. Read more

Genome engineering and centromere diversity

Centromeres are the DNA sequences that are responsible for accurate segregation of eukaryotic chromosomes at cell division. Although centromeres mediate a conserved function they are remarkably diverse in evolution. Read more

Isolation and characterization of matrix bound vesicles for bone repair

Extracellular matrix (ECM) derived biomaterials have been used in more than 8 million patients worldwide. Yet, the mechanisms by which ECM biomaterials modulate cell behaviour are not fully understood. Read more

Mathematical modelling of oral microbiome resilience

Maintenance of oral health is essential. It is known that the microbiome, host response, and human behaviours (e.g. tooth brushing) play an essential role in maintaining oral health. Read more

Development of molecular simulation model for heterogeneous RNA and RNA-protein structures.

In recent years, it has become clear that RNA molecules play active roles in a variety of cell regulatory processes. In addition, RNA molecules have a great potential for therapeutic applications, as evidenced by the success of COVID-19 mRNA vaccines. Read more

Unlocking the potential of a novel microtubule growth inhibitor as a cancer therapeutic

Microtubules are a functionally versatile and critically important component of the cytoskeleton and as a result have been one of the most actively pursued therapeutic targets of the past 60 years. Read more

Characterising blood-brain barrier formation and function using zebrafish to understand human vascular hyperpermeability

The blood-brain barrier (BBB) is a highly selectively permeable network of blood vessels within the brain. This barrier is essential for central nervous system (CNS) homeostasis by controlling molecular flux between the blood and the brain and protecting it from pathogens and toxins. Read more

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