We have 4 Cancer Biology PhD Projects, Programmes & Scholarships in Nottingham

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Nottingham  United Kingdom

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Cancer Biology PhD Projects, Programmes & Scholarships in Nottingham

We have 4 Cancer Biology PhD Projects, Programmes & Scholarships in Nottingham

University of Nottingham

Research that changes lives and shapes the future

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Structural biology tools to investigate and target ubiquitin system proteases in cancer

University of Nottingham School of Pharmacy
Ubiquitination targets proteins for degradation and regulates virtually all cellular signalling pathways in eukaryotes. The human genome encodes over 50 ubiquitin specific proteases (USPs) that cleave ubiquitin from modified proteins to salvage them from proteasomal degradation. Read more
 Supervisor: Dr I Dreveny
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy
Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more
 Supervisor: Dr G S Winkler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Role of BTG1 and BTG2 in acute lymphocytic leukaemia and diffuse large B-cell lymphoma

University of Nottingham School of Pharmacy
Acute lymphocytic leukaemia (ALL) and diffuse large B-cell lymphoma (DLBCL) is often associated with small deletions of or point mutations in the highly related BTG1 or BTG2 genes. Read more
 Supervisor: Dr G S Winkler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy
Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more
 Supervisor: Dr G S Winkler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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