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Cancer / Oncology PhD Projects, Programs & Scholarships in Nottingham

We have 9 Cancer / Oncology PhD Projects, Programs & Scholarships in Nottingham

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Showing 1 to 9 of 9
  The role of the p53 co-factor JMY in the regulation of gene expression in human cancer
  Dr A Coutts
Application Deadline: 4 April 2019
Tumour growth is achieved by overriding cell cycle control and bypassing cell death mechanisms. Mechanisms influencing cell survival such as apoptosis and autophagy are key determinants of cell fate during stress.
  A new paradigm for cancer vaccine delivery: Intradermal lymphatic targeting
  Dr M Marlow
Application Deadline: 1 March 2019
Numerous approaches have been undertaken to develop ways of stimulating the cellular immune response to eradicate tumours, known as cancer vaccines or immunotherapy.
  Biomolecular Science and Medicinal Chemistry Division PhD project: Proteases in the ubiquitin system – from molecular mechanisms to the development of novel inhibitors
  Dr I Dreveny
Applications accepted all year round
Ubiquitin is a posttranslational modifier that tags substrate proteins for degradation and regulates virtually all known cellular processes.
  Structure and function of enzyme complexes involved in post-transcriptional gene regulation
  Dr G S Winkler
Applications accepted all year round
Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics.
  Role of BTG1 and BTG2 in acute lymphocytic leukaemia and diffuse large B-cell lymphoma
  Dr G S Winkler
Applications accepted all year round
Acute lymphocytic leukaemia (ALL) and diffuse large B-cell lymphoma (DLBCL) is often associated with small deletions of or point mutations in the highly related BTG1 or BTG2 genes.
  Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes
  Dr G S Winkler
Applications accepted all year round
Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease.
  Cryo electron microscopy to study innate immune complexes on the surface of cancer cells
  Dr J Emsley
Application Deadline: 31 May 2019
Blood vessels of tumors carry specific markers on the cell surface. The innate immune system consisting of complement proteins and white blood cells (macrophages) are involved in the recognition and destruction of cancer cells.
  CRISPR CAS9 Genome Editing to Study PIP5K1A in Cancer Cells
  Prof D Heery
Applications accepted all year round
Human PIP5K1A is one of a family of kinases that generate the signalling molecule phosphatidylinositol 4,5-bisphosphate (PIP2) in cells.
  Investigation of long-term sensory neuronal degeneration and pain in adult childhood cancer survivors
  Dr RP Hulse
Applications accepted all year round
Advances in childhood cancer research has led to increased understanding and early diagnosis of cancer, has led to a significant increase in childhood cancer survivorship.
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