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Pharmacology / Toxicology PhD Projects, Programs & Scholarships in Nottingham

We have 10 Pharmacology / Toxicology PhD Projects, Programs & Scholarships in Nottingham

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  The impact of pain on the aging nervous system
  Dr G Hathway
Applications accepted all year round

Funding Type

PhD Type

The way in which pain is detected and processed changes significantly over the life-course.
  Characterisation of novel inhibitors of vascular injury due to inflammation
  Dr V Ralevic
Applications accepted all year round

Funding Type

PhD Type

Myeloperoxidase (MPO) is a haemoprotein that is highly expressed in neutrophils and is secreted during injury and inflammation to assist in host defence reactions by producing antimicrobial reactive oxygen species.
  Hydrogen sulphide as a treatment for respiratory disease.
  Dr R Roberts, Dr SPH Alexander
Applications accepted all year round

Funding Type

PhD Type

We have demonstrated that hydrogen sulphide (H2S) is synthesised within the airways in the lungs. H2S synthesis in the airways occurs through activation of the enzymes cystathionine  lyase, cystathionine β synthase, and mercaptopyruvate sulphurtransferase (MPST).
  Understanding structure and drug binding in the multidrug pump ABCG2
  Dr I Kerr, Dr R Layfield
Applications accepted all year round

Funding Type

PhD Type

ABCG2 is one of three human ATP binding cassette transporters that are functionally capable of exporting a diverse range of substrates from cells.
  Targeting antiretroviral drugs to the gut-associated lymphoid tissues for improved treatment of HIV/AIDS
  Dr P Gershkovich
Applications accepted all year round

Funding Type

PhD Type

"Gut-associated lymphoid tissue (GALT) is an anatomical reservoir of HIV, setting a barrier for strategies aimed at HIV eradication.
  Targeting cannabinoids to the gut-associated lymphoid tissue (GALT) for improved treatment of autoimmune diseases
  Dr P Gershkovich
Applications accepted all year round

Funding Type

PhD Type

Autoimmune diseases are conditions that are triggered by the immune system initiating an attack on the body’s own molecules. The causes of such attacks in most cases are unknown, but a number of studies suggest that they are associated with factors such as genetics, infections and environment.
  Targeting anticancer drugs to the intestinal lymphatic system for improved treatment of cancer
  Dr P Gershkovich
Applications accepted all year round

Funding Type

PhD Type

The lymphatic system plays an important role in the pathophysiology of cancer as it can be both a site for the primary cancer and the major route of metastasis.
  15 fully-funded 4-year PhD studentships in the EPSRC Centre for Doctoral Training in Transformative Pharmaceutical Technologies

Funding Type

PhD Type

Funded by the Engineering and Physical Sciences Council, Science Foundation Ireland and 19 industry partners, the EPSRC Centre for Doctoral Training (CDT) in Transformative Pharmaceutical Technologies provides world-leading training to prepare strategic-thinking scientists for high achieving careers in the pharmaceutical and healthcare sectors.
  Biomolecular Science and Medicinal Chemistry Division PhD project: Proteases in the ubiquitin system – from molecular mechanisms to the development of novel inhibitors
  Dr I Dreveny
Applications accepted all year round

Funding Type

PhD Type

Ubiquitin is a posttranslational modifier that tags substrate proteins for degradation and regulates virtually all known cellular processes.
  Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes
  Dr G S Winkler
Applications accepted all year round

Funding Type

PhD Type

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease.
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