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Nottingham×
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Structural Biology PhD Projects, Programs & Scholarships in Nottingham

We have 4 Structural Biology PhD Projects, Programs & Scholarships in Nottingham

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  Biomolecular Science and Medicinal Chemistry Division PhD project: Proteases in the ubiquitin system – from molecular mechanisms to the development of novel inhibitors
  Dr I Dreveny
Applications accepted all year round
Ubiquitin is a posttranslational modifier that tags substrate proteins for degradation and regulates virtually all known cellular processes.
  Structure and function of enzyme complexes involved in post-transcriptional gene regulation
  Dr G S Winkler
Applications accepted all year round
Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics.
  Cryo electron microscopy to study innate immune complexes on the surface of cancer cells
  Dr J Emsley
Application Deadline: 31 May 2019
Blood vessels of tumors carry specific markers on the cell surface. The innate immune system consisting of complement proteins and white blood cells (macrophages) are involved in the recognition and destruction of cancer cells.
  Understanding structure and drug binding in the multidrug pump ABCG2
  Dr I Kerr, Dr R Layfield
Applications accepted all year round
ABCG2 is one of three human ATP binding cassette transporters that are functionally capable of exporting a diverse range of substrates from cells.
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