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The University of Manchester, Faculty of Biology, Medicine and Health Obstetrics, Gynaecology & Reproduction PhD Projects, Programs & Scholarships

We have 8 The University of Manchester, Faculty of Biology, Medicine and Health Obstetrics, Gynaecology & Reproduction PhD Projects, Programs & Scholarships

  • Obstetrics, Gynaecology & Reproduction×
  • The University of Manchester
  • Faculty of Biology, Medicine and Health×
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  (BBSRC DTP) Understanding the contribution of dietary extracellular vesicles to healthy human development
  Prof M Westwood, Dr L Harris, Prof A Nicolaou, Dr A Stevens
Application Deadline: 31 January 2020

Funding Type

PhD Type

The ability to adapt behaviour in response to nutrient availability is important for all cells but particularly so for trophoblasts, as these cells form the placenta - the interface between mother and fetus - and act as fetal sentinels of the maternal environment.
  (BBSRC DTP) Using markers of gene evolutionary age to identify function within gene regulatory networks related to embryo implantation
  Prof D Brison, Dr A Stevens, Dr Peter Ruane, Prof M Westwood
Application Deadline: 31 January 2020

Funding Type

PhD Type

Successful implantation relies upon synchrony between a competent blastocyst and receptive endometrium. Molecular networks mediating these events at implantation are not well understood in humans.
  Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Applications accepted all year round

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  Exploration and treatment of sFlt-mediated cardiac dysfunction in animal model of preeclampsia (Manchester-Melbourne Dual Award)
  Dr J Myers, Dr E Johnstone
Application Deadline: 31 January 2020

Funding Type

PhD Type

Our project “Exploration and treatment of sFlt-mediated cardiac dysfunction in animal model of preeclampsia” provides an exciting opportunity for a student interested in maternal and fetal health to learn and develop new techniques in two world leading centres that are focused on translating laboratory experiments into improvements in clinical care.
  Investigating the mechanisms contributing to placental dysfunction in pregnancies complicated by diabetes: role of the hexosamine biosynthetic pathway
  Prof M Westwood, Prof J Aplin, Dr J Myers
Applications accepted all year round

Funding Type

PhD Type

Maternal diabetes is a major risk factor for fetal overgrowth, which is associated with poor outcomes including stillbirth, neonatal morbidity and increased risk of diabetes in adulthood.
  Is there a switch between prostamides and prostaglandins in women with dysmenorrhoea and heavy menstrual bleeding?
  Prof K Marshall, Dr D Fischer, Prof A Nicolaou
Applications accepted all year round

Funding Type

PhD Type

Dysmenorrhoea, painful menstrual cramps, and heavy menstrual bleeding are common debilitating symptoms in women with or without an underlying pelvic pathology.
  Phenotyping placental disease in women with diabetes and chronic hypertension using transcriptomic analysis
  Dr J Myers, Dr E Johnstone
Applications accepted all year round

Funding Type

PhD Type

Placental disease triggers medically-indicated preterm birth in 1 in 6 pregnancies complicated by chronic hypertension and/or diabetes (cardiometabolic disease).
  Understanding the impact of placental aging on placental function
  Dr A Heazell, Dr M Dilworth, Dr M Desforges
Applications accepted all year round

Funding Type

PhD Type

Prolonged pregnancy (>41 weeks gestation) is associated with an increase in perinatal mortality (the death of a baby before or shortly after birth) from a nadir of 1 per 1,000 births at 39 weeks’ to 3 per 1,000 births at 41 weeks which continues to rise beyond this time.
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