This project will generate human retinal ganglion cells (RGCs) for therapeutic testing. We will replace mouse tissue with human RGCs differentiated from patient-derived induced pluripotent stem cells (hiPSCs) from dominant optic atrophy caused by mutation in the OPA1 gene and from normal controls. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Our ultimate purpose is to work in service of patients. RCSI was founded by Royal Charter on 11th February 1784, to set and support professional standards for surgical training and practice in Ireland. Read more
Some or all of the PhD opportunities in this programme have funding attached. Applications for this programme are welcome from suitably qualified candidates worldwide. Funding may only be available to a limited set of nationalities and you should read the full programme details for further information.
An Irish PhD usually takes 3-4 years. Traditional doctorates focus primarily on independent research; structured programmes include additional classes and a greater focus on transferable skills. Most students initially register for an MPhil degree before upgrading to the status of PhD candidate and completing their thesis. This will be assessed through an oral viva voce process involving two examiners.
Inherited developmental disorders account for much of childhood visual impairment. Development of the eye requires cell fate decisions that balance stem cell proliferation and differentiation. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Research interests/description of main research theme. Mitochondria are fundamental for tissue homeostasis, by regulating central processes involved in metabolism, oxidative stress and cell death. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This research project has funding attached. It is only available to UK citizens or those who have been resident in the UK for a period of 3 years or more. Some projects, which are funded by charities or by the universities themselves may have more stringent restrictions.
Background. Age-related macular degeneration (AMD) is the leading cause of impaired vision and blindness in over 50s for which treatments are limited to a small subset of sufferers. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Mutations resulting in haploinsufficiency or hypomorphic alleles are the cause of most inherited retinal dystrophies (IRDs). Gene replacement therapy for such conditions is one treatment option but the large developmental costs and time associated with such therapies are barriers to developing this approach more widely. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.