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Organic Chemistry (human) PhD Projects, Programs & Scholarships

We have 23 Organic Chemistry (human) PhD Projects, Programs & Scholarships

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  Deciphering acetaldehyde biochemistry using small molecule tools: from hangovers to cancer (GTA 20 HOP)
  Dr J Hodgkinson, Dr S Handa
Application Deadline: 4 February 2020

Funding Type

PhD Type

Acetaldehyde, the first product of ethanol metabolism, is a human toxin and carcinogen. Many of the intoxicating and disease-inducing effects of drinking alcohol, as well as the symptoms of hangovers, are likely due to acetaldehyde.
  Discovery of novel pharmaceuticals from marine and desert microorganisms
  Prof M Jaspars, Dr R Ebel
Applications accepted all year round

Funding Type

PhD Type

Microorganisms from extreme environments such as the deep seas, cold seas and hyper arid deserts have been shown to produce a range of complex natural products with high biological activity.
  Designing novel composite polysaccharide nanoparticles for combined diagnosis and treatment of cancers
  Dr E Barbu, Dr A Lalatsa
Applications accepted all year round

Funding Type

PhD Type

Cancer continues to impose a vast burden with regard to financial costs as well as human suffering but the progress in its treatment is hindered by the limited selectivity and significant side-effects that the current chemotherapy demonstrates, representing a major challenge for modern drug delivery.
  Characterisation and quantification of O6-alkylguanine adducts in DNA for clinical assessment of cancer risk
  Dr D Williams
Application Deadline: 5 February 2020

Funding Type

PhD Type

Exposure of DNA to alkylating agents can produce alkylated DNA base adducts that induce mutations (base changes) following DNA replication.
  Developing an enzymatic toolbox to make complex modified peptides
  Prof M Jaspars, Dr W Houssen, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

The pharmaceutical industry has identified a major gap in its portfolio. On the one hand, they are excellent at discovering small molecules that act via a lock and key type mechanism.
  Genome mining of novel antimicrobial natural products from new bacterial strains
  Dr H Deng, Prof M Jaspars
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Inhibitors of viral methyltransferases
  Dr R Nencka
Application Deadline: 23 February 2020

Funding Type

PhD Type

Viral methyltransferses (MTases) play an essential role in the capping of the newly synthesized viral RNA during the replication process.
  PhD Studentship: Detection of peroxynitrite using a reactive luminescent lanthanide probe
  Dr S Butler
Application Deadline: 22 August 2020

Funding Type

PhD Type

Application details. Reference number. CM/SJB-Un1/2020. Start date of studentship. 1st October 2020. Closing date of advert. 22th August 2020.
  FoodBioSystems DTP - Nitrosamine formation and colorectal cancer (CRC) risk in processed meats: investigating the role of nitrites, extraneous nitrates and possible nitrite replacers
  Dr B Green, Dr A Nugent, Dr G Kuhnle
Application Deadline: 6 March 2020

Funding Type

PhD Type

Research Group. FOODBIOSYSTEMS BBSRC DTP. Processed meat intake has been associated with an increased risk of colorectal cancer, and in 2015 the WHO has categorised processed meat as “carcinogenic to humans”.
  Chemical and enzymatic tools for pathogen glycobiology
  Prof R Field, Prof S Flitsch
Application Deadline: 31 January 2020

Funding Type

PhD Type

Dual-award between The University of Manchester and The University of Melbourne. This dual-award programme offers candidates the opportunity to apply for a project with a strong supervisory team both in Manchester and in Melbourne.
  Synthesis and computation to understand and redesign self-assembling carbohydrate materials
  Prof R Field, Dr A Almond
Application Deadline: 31 January 2020

Funding Type

PhD Type

Polysaccharides are widespread in nature and fulfil many important biological functions; they are important foodstuffs and they are exploited as bulk commodities across industry sectors due to their physical properties.
  Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics
  Dr L Wong, Dr C F Blanford
Applications accepted all year round

Funding Type

PhD Type

Plastics are a broad range of solid polymeric materials that have found widespread application as industrial components and consumer goods.
  (BBSRC DTP) Synthesis and identification of highly efficient polymeric nanoparticles for transfection of cells
  Research Group: Polymers and Composites
  Dr S Jones, Prof M Shaver
Application Deadline: 31 January 2020

Funding Type

PhD Type

Gene therapy transfers genetic material into cells to provide new functions, including as potential interventions and treatments for a wide range of human diseases.
  (BBSRC DTP) Selective knockdown of proinflammatory microRNAs to tackle neurodegeneration and cognitive decline: myth or reality?
  Dr E Bichenkova, Prof J Neill, Dr F Roncaroli, Prof D Clarke
Application Deadline: 31 January 2020

Funding Type

PhD Type

Neurodegenerative diseases (e.g. multiple and amyotrophic lateral sclerosis, Alzheimer’s and Parkinson’s diseases) have tremendous psychological, clinical and social impact, which becomes increasingly challenging in the global trend of population aging.
  Tyrosine kinase inhibitors conjugated tumour targeting dyes for the treatment of glioblastoma.
  Dr J Jose, Dr P Choi
Applications accepted all year round

Funding Type

PhD Type

Glioblastoma (GBM) remains a lethal and difficult to treat cancer with a dismal outcome. Although we have a better understanding of the disease progression, a concurrent increase in therapeutic intervention is lagging.
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