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University of Manchester Organic Chemistry PhD Projects, Programs & Scholarships

We have 23 University of Manchester Organic Chemistry PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 23
  (BBSCR DTP) Design of allosteric small molecule probes of fibrosis using molecular dynamics simulations
  Dr R A Bryce, Dr K Piper Hanley, Dr R Whitehead
Application Deadline: 31 January 2019
Integrins are a family of protein receptors that play a major role in cell survival, growth and migration. Their function is to transmit signals across the cell membrane by undergoing an elegant large scale structural rearrangement.
  (BBSRC DTP) Development of a toolkit of bi-substrate modulators of signalling pathways
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Application Deadline: 31 January 2019
Protein phosphatases control key events in cell physiology and adaptation to the environment, and are critically involved in fundamental biological processes such as development, cell division and homeostasis.
  (BBSRC DTP) Isothermal Amplification for viral detection
  Dr S Jones, Prof P Vallely
Application Deadline: 31 January 2019
The need to develop better techniques capable of improving detection of viral infections, whilst also improving the assays associated with identifying suitable antivirals is of upmost importance.
  Identification of novel anticonvulsant compounds
  Prof R Baines, Dr S Freeman, Prof S Allan
Applications accepted all year round
Epilepsy and other associated seizures are a significant health concern, occurring in an estimated 1-2% of the world’s population.
  Structure based design of novel warheads for use in peptide-drug conjugates
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round
Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
  Understanding and Developing Student Preparedness: Investigating Behaviour and Performance Characteristics of Students During Activity Preparation
  Dr T L Rodgers
Applications accepted all year round
Professional bodies and institutions are currently advising universities to innovate in their teaching and learning practices, and align their teaching with pedagogy, in order to produce high quality graduates.
  (BBSRC DTP CASE) A synthetic biology approach to develop bacterial protein expression tools
  Prof J Micklefield, Dr A Green
Application Deadline: 31 January 2019
Streptomyces and related bacteria possess diverse biosynthetic pathways that produce a wide array of bioactive natural compounds including antibiotics, anti-cancer agents and other therapeutically important molecules.
  (BBSRC DTP CASE) Driving enzymatic carboxylation using supercritical CO2
  Prof D Leys, Dr S Hay, Prof I Larrosa
Application Deadline: 31 January 2019
The use of CO2 as a chemical feedstock is attractive for various reasons, not least as a means to address the desirable reduction of global CO2 levels.
  (BBSRC DTP) Characterization of P450 peroxygenases and their applications in alkene/biofuel production
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2019
The project involves characterization of P450 peroxygenase enzymes, a class of the P450 enzymes which naturally use hydrogen peroxide rather than redox partner systems to drive catalysis.
  (BBSRC DTP) Design and Evolution of Enzymes with Non-Canonical Organocatalytic Mechanisms
  Dr A Green, Prof D Leys, Dr S Hay
Application Deadline: 31 January 2019
The project is firmly embedded at the interface of chemistry, biology and biophysics, a key driver for the BBSRC in the ‘Exploiting new ways of working’ agenda.
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