This full-time DPhil post at the Botnar Institute will use cutting edge laboratory and computational methods to interrogate the mechanisms underlying shoulder pain. Read more
The Engineering and Physical Sciences Research Council (EPSRC) is the main UK government agency for funding research and training in engineering and the physical sciences, investing more than £800 million a year in a broad range of subjects - from mathematics to materials science, and from information technology to structural engineering. Read more
Fibrotic diseases affect multiple organ systems, increasing global morbidity and mortality1. Fibrosis is the final common pathway for a wide range of diseases affecting joint soft tissues including tendons, ligaments and synovial tissues2,3. Read more
mRNA based technologies have revolutionised vaccines and have the potential to modulate not just immunity to pathogens but also re-engineer immune responses to resolve chronic inflammatory disease. Read more
Rheumatoid arthritis (RA) is an immune mediated inflammatory disease which constitutes a major global healthcare challenge as it causes significant disability and pain. Read more
This full-time DPhil post at the Botnar Institute will use cutting edge laboratory and computational methods to interrogate the mechanisms underlying failed repair following scaphoid fracture. Read more
Patient-reported outcomes are included in randomised clinical trials (RCTs) as primary or secondary endpoints to measure the impact of interventions and are increasingly recognised by regulators, clinicians, and patients as valuable tools that ensure comprehensive assessment. Read more
Fibrotic diseases affect multiple organ systems, increasing global morbidity and mortality1. Fibrosis is a final common pathway for a wide range of diseases affecting musculoskeletal tissues. Read more
This DPhil project aims to elucidate the mechanisms of RNA splicing within immune cells, focusing on the computational analysis of alternative splicing events and their impact on immune homeostasis and inflammatory responses. Read more
Adverse drug reactions (ADRs) are unintended, harmful events attributed to the use of medicines. In modern healthcare, ADRs pose a significant challenge due to the complexity of therapeutics, an aging population, and rising multimorbidity. Read more
Immune cells play a fundamental role in health and disease. We are applying the latest molecular and cellular multi-omics analysis platforms (single-cell and spatial omics) and computational methods to deliver insights into immune cell biology across a range of human tissues (e.g. Read more
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