Prof R Thakker, Dr K Lines, Dr M Stevenson, Dr K Kooblall
26 July 2019
Other Potential Supervisors. Dr Asha Bayliss. The Academic Endocrine Unit investigates the molecular basis of endocrine and metabolic disorders that principally affect calcium and phosphate homeostasis.
In the Sahakyan Group, we strive to make computational biology maximally independent from empirical experimental data, by basing our models and predictions on genomic sequences and core biological mechanisms.
The group uses a combination of deep learning, stochastic models and Bayesian modelling to study questions relating to stem cell fate dynamics and how mutations in stem cells alter their normal behaviour, become fixed and accumulate in the tissue eventually leading to cancer.
Our DNA is constantly under threat from damaging agents. If unrepaired this DNA damage can lead to errors during genome duplication, including the mutations that can lead to cancer and other human diseases.
Dr H Koohy, Prof V Cerundolo, Prof T Dong, Prof A Simmons
26 July 2019
Cancer immunology is an area of cancer research that is gaining tremendous momentum. However, responses to immunotherapy are heterogeneous and patient care could be substantially improved by better understanding of how and why responses to immunotherapeutic approaches vary in different patients.