or
Continue with FacebookLooking to list your PhD opportunities? Log in here.
We have 138 PhD Projects, Programmes & Scholarships for Self-funded Students in Oxford
PhD Projects, Programmes & Scholarships for Self-funded Students in Oxford
We have 138 PhD Projects, Programmes & Scholarships for Self-funded Students in Oxford
P19. Combatting Antimicrobial Resistance (CSHP CDT)
Resistance to pharmaceuticals, including anti-infectives and cancer drugs, and agrochemicals is a major global health problem. As highlighted by the 2016 O’Neill report, the situation with current antibiotics is perilous. Read more
P18. Synthesis of Aryl-fused Bicyclo[3.1.1]heptanes (BCHeps) and Validation as Heterobiaryl Bioisosteres (CSHP CDT)
While naphthalene and equivalent heterobiaryl rings are often encountered in drugs, candidates and lead molecules, they can be susceptible to cytochrome P450-mediated metabolism and exhibit flat, sp2-rich structures and are almost invariably derived from fossil fuel sources, limiting their current and future utility. Read more
P15. Sustainable Hydrogen Borrowing Catalysis with Earth Abundant Metals (CSHP CDT)
While hydrogen borrowing (HB) catalysis offers an attractive route for the construction of C-C bonds using alcohols and ketones, current methods rely upon expensive precious metal catalysts. Read more
P24. Metal catalysis for the sustainable synthesis of pharmaceutically relevant heterocycles (CSHP CDT)
Functionalised heterocycles remain the cornerstone of medicinal chemistry programmes, and in particular, heterocycles linked to a second heterocycle or other aromatic group, feature prominently. Read more
P5. New metal-free catalysts for organic synthesis (CSHP CDT)
The design of new non-precious metal catalysts and organic catalysts is key to modern reaction innovation and sustainability. This project will involve, the design and synthesis of a new range of chiral organocatalysts bearing chiral heteroatoms. Read more
P8. Computational Design of Macrocycle Compounds (CSHP CDT)
Macrocyclic compounds have emerged as a promising alternative to small molecules against difficult-to-treat targets. However, challenges in their synthesis, in particular with regards to cyclisation have hindered further discovery. Read more
P14. Next generation antibiotic siderophores (CSHP CDT)
This project will develop next generation synthetic siderophores - small molecule high affinity iron receptors used by bacteria to accumulate iron. Read more
P23. Polymers From Carbon Dioxide: Using Precision Catalysis to Control Polymer Properties (CSHP CDT)
Polymer manufacturing is already responsible for 1.6 Gt CO2 equiv. emissions annually, recent academic study reveals that replacing petrochemical raw materials with biomass, carbon dioxide and waste polymers can help to drive down these emissions enabling net zero targets. Read more
P13. Micellar organo-catalysis in water using earth abundant main group elements (CSHP CDT)
This project will explore methods to use earth abundant, Lewis acidic main group catalysts to catalyse organic transformations in water by exploiting micellar confinement. Read more
P11. The development of photodynamic surfactants: a new modality to tackle anti-microbial resistance (CSHP CDT)
There is increasing interest in the use of surfactants to tackle key elements of antimicrobial resistance (AMR). Read more
P9. Electrochemical control over oscillating chemical reactions (CSHP CDT)
Out-of-equilibrium chemical processes related to synthetic chemistry are not well understood. We have developed oscillating chemical reactions, which involve both molecular and supramolecular (micelles, vesicles, etc) oscillations, and may serve as the basis for developing new processes. Read more
P1. Improving the sustainability of propellane chemistry (CSHP CDT)
Bicyclo[n.1.1]alkanes (BCAs) have emerged as important building blocks in contemporary drug design, serving as useful building blocks that can substitute for aromatic rings, leading to improved physicochemical and pharmacokinetic profiles of drug candidates. Read more
P25. The catalytic synthesis of sulfonamide and sulfonimidamide building blocks from simple feedstocks (CSHP CDT)
Sulfur derived functional groups are found in medicinal agents used to treat to broad range of indications. Sulfonamides are most common group, featuring in >10% of medicines. Read more
P22. CO2 and Bio-derived Oxygenated Polymers to Reduce Adhesives Carbon Footprint (CSHP CDT)
Adhesives play a critical role in many technologies from construction, transportation, electronics to consumer goods. There are growing environmental concerns, legislation and customer pressure to deliver more sustainable adhesives and to ensure they maximise recycling of other components. Read more
P21. Radical polar crossover from the triplet state (CSHP CDT)
New reaction manifolds are valuable for the synthesis of complex molecules. This project will focus on the development of radical-polar crossover reactions by employing visible light mediated energy transfer catalysis to generate complex three-dimensional heterocyclic scaffolds. Read more