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We have 11 Structural Biology PhD Projects, Programmes & Scholarships in Oxford
Structural Biology PhD Projects, Programmes & Scholarships in Oxford
We have 11 Structural Biology PhD Projects, Programmes & Scholarships in Oxford
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Molecular mechanisms of influenza virus replication
Our laboratory focuses on elucidating the fundamental molecular mechanisms underlying the replication of RNA viruses such as Influenza, Nipah, and SARS-CoV-2. Read more
Rhomboid-like proteins: from molecular principles to their role in human disease
The questions we address deal with the molecular mechanisms that underlie signalling between cells, and cellular responses to stress. Read more
Cryo-EM of Transport Complexes that Build the Cell’s Antenna
A major question in structural cell biology is how micrometer-scaled organelles are constructed and maintained. Cilia, also known as eukaryotic flagella, are multifunctional organelles that emanate from almost all cell types in the human body and many other eukaryotes. Read more
Molecular mechanisms of genome stability and cancer
The maintenance of complete and undamaged genome is critical for survival. However, DNA is a fragile structure susceptible to DNA damage. Read more
Regulation of genome stability and human disease
Poly(ADP-ribose) polymerases (PARPs) are the major family of enzymes that synthesize an abundant posttranslational protein modification called ADP-ribosylation. Read more
Transport to the bacterial outer membrane: building a barrier that confers antimicrobial resistance.
Antimicrobial resistant (AMR) micro-organisms cause a major global threat to modern medicine, contributing to almost 5 million deaths a year. Read more
Mechanistic studies on protein folding and assembly of ciliary dynein motors.
All proteins are made up of amino acids, the building blocks of cells, which are strung together to make a peptide chain. Polypeptide chains get sculpted into their 3‐dimensional shapes to specify a cellular function by additional proteins called molecular chaperones and assembly factors. Read more
A Novel K+ Channel Target (KCNK13/THIK1) for Neurodegenerative Disorders: Understanding its mechanism of inhibition by small molecule drugs and biological therapeutics
Commercial partner: Cerevance. The student will be involved in an exciting multidisciplinary project aimed at determining the structural and molecular mechanisms of a range of novel inhibitors of the THIK1 K2P K+ channel. Read more
The Department of Oncology at the University of Oxford
The Department of Oncology employs multidisciplinary approaches from physics, biology, chemistry and mathematical modelling to investigate DNA biology and epigenetics, cell and environmental biology of tumour tissue, and both systemic and local immunological responses in cancer. Read more
Mechanisms of protein quality control in health and disease
Accumulation of misfolded proteins and aberrant protein aggregates are hallmarks of a wide range of pathologies such as neurodegenerative diseases and cancer. Read more
Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research (EPSRC Centre for Doctoral Training)
We welcome applications from graduates who wish to make an impact in the field of computational biomedical research. Our students gain the broad skillset needed to confront current and future biomedical research challenges. Read more
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