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Parasitology (complex systems) PhD Projects, Programs & Scholarships

We have 6 Parasitology (complex systems) PhD Projects, Programs & Scholarships

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  Identification of the Trypanosoma brucei transferrin receptor-recognition site of transferrin (SteverdingDU19SF)
  Dr D Steverding
Application Deadline: 31 May 2020

Funding Type

PhD Type

The transferrin receptor of the protozoan parasite Trypanosoma brucei (TbTfR) is a heterodimeric protein complex encoded by two expression site associated genes, ESAG6 and ESAG7, which shows no homology to the homodimeric human transferrin receptor (hTfR).
  EASTBIO Molecular basis of environmental sensing in fungi and protozoan parasites
  Research Group: Institute of Immunology & Infection Research
  Dr J Thompson, Dr J Baranovic, Dr E Wallace
Application Deadline: 5 January 2020

Funding Type

PhD Type

Many of the unicellular eukaryotic parasites that cause disease in humans are exquisitely adapted to navigate the complex and dynamic environments that they encounter in their hosts in order to sustain their life cycles and spread infection.
  How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function
  Dr K Couper, Prof R K Grencis
Applications accepted all year round

Funding Type

PhD Type

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state.
  Genome-wide responses to stress
  Dr J Mata
Applications accepted all year round

Funding Type

PhD Type

We are interested in gene regulation in responses to stress, using both simple model organisms, human and plant pathogens. Cells respond to stress conditions by launching complex programs of gene expression, both transcriptional and posttranscriptional, and which are often closely linked with each other.
  EASTBIO Exploiting synthetic DNA binding proteins to target and define the epigenetic characteristics of distinct Trypanosoma brucei chromosomal regions
  Research Group: Institute of Cell Biology
  Prof R Allshire, Prof K Matthews
Application Deadline: 5 January 2020

Funding Type

PhD Type

Kinetoplastid parasites are major pathogens responsible for important tropical diseases including Chagas disease, Leishmaniasis and African trypanosomiasis.
  EASTBIO The genetic basis of helminth-specific immune responses in wild Soay sheep (Ovis aries)
  Research Group: Institute of Evolutionary Biology
  Dr S Johnston, Dr T McNeilly, Prof D Nussey
Application Deadline: 5 January 2020

Funding Type

PhD Type

Individual differences in immune responses are widely observed in nature and are likely to be a major factor underlying variation in disease resistance, health and evolutionary fitness.
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