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The University of Manchester, Faculty of Biology, Medicine and Health Parasitology PhD Projects, Programs & Scholarships

We have 4 The University of Manchester, Faculty of Biology, Medicine and Health Parasitology PhD Projects, Programs & Scholarships

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  (BBSRC DTP) Developing a whipworm vaccine composed of virus-like particles expressing Trichuris T cell epitopes
  Prof K Else, Prof J P Derrick
Application Deadline: 31 January 2020

Funding Type

PhD Type

Vaccination is one of the greatest advances in global health; however most successful vaccines have been made empirically. We still have little insight into how many vaccines work and the mechanisms by which they trigger protective immune responses.
  Environmental control of dendritic cell activation and function during pulmonary type 2 inflammation
  Prof A MacDonald, Prof J Allen
Applications accepted all year round

Funding Type

PhD Type

Type 2 inflammation is a defining feature of infection with parasitic worms (helminths), as well as being responsible for widespread suffering in allergies.
  How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function
  Dr K Couper, Prof R K Grencis
Applications accepted all year round

Funding Type

PhD Type

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state.
  Ultrastructural analysis of the mouse whipworm as a model for human trichuriasis
  Prof R K Grencis, Dr T Starborg
Applications accepted all year round

Funding Type

PhD Type

Gastrointestinal dwelling nematode parasites are extremely successful parasites of both man and animals infecting over a billion people worldwide and are responsible for considerable morbidity and ill health worldwide.
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