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We have 24 Pathology (cell culture) PhD Projects, Programmes & Scholarships

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Pathology (cell culture) PhD Projects, Programmes & Scholarships

We have 24 Pathology (cell culture) PhD Projects, Programmes & Scholarships

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Study of early pathological changes in calcified cartilage in osteoarthritis and alkaptonuria

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
We are seeking a motivated individual to work on this exciting project investigating the role that the calcified cartilage has in rare and common joint osteoarthritis, using novel approaches such as gene silencing and establishment of a 3D chondrocyte cell culture model. Read more
 Supervisor: Dr JH Hughes
 10 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry
Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more
 Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

University of Dundee School of Medicine
Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more
 Supervisor: Dr M Mclean
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Elucidation of a new pathological mechanism for brittle bone disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
The incidence of the brittle bone disease osteogenesis imperfecta (OI) is estimated to be around 1 in 10,000 individuals. The phenotypic spectrum of OI ranges from mild to perinatal lethal and includes extra-skeletal connective tissue manifestations. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute
Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more
 Supervisors: Dr M Secrier, Dr L Cottone
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health
The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more
 Supervisors: Dr MM Mennon, Prof MH Buch
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health
Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more
 Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer Neuroscience: Investigating the impact of non-CNS tumours on neuronal plasticity in the brain

University of Nottingham School of Life Sciences
Cancer is one of the leading causes of death worldwide, resulting in approximately 18 million new cases and 10 million deaths each year. Read more
 Supervisor: Dr G Sheridan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of extracellular vesicles and intercellular signalling in inherited kidney cancer

Cardiff University Cardiff School of Medicine
This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£60,000 total). Read more
 Supervisor: Dr E Dunlop
 31 May 2024  PhD Research Project  Self-Funded PhD Students Only
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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

University of Greenwich School of Pharmacy (Medway Campus)
Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more
 Supervisor: Dr S Ashraf
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Preventing Prostate Cancer, and Related Metastases

Medical University of Vienna Institute for Pathophysiologie and Allergy
The goal of this project is to elucidate the role of the thyroid hormone pathway for prognosis and therapy response of prostate cancer (PCa). Read more
 Supervisor: Dr L Kenner
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Investigating the genetic determinants of ultra-complex telomere fusion

Cardiff University Cardiff School of Medicine
We are seeking a motivated molecular biologist to study the mechanisms by which telomere dysfunction impacts cancer genomes. Read more
 Supervisor: Prof D Baird
 3 May 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Development of new molecular therapies to treat motor neuron disease (MND)

Macquarie University Centre for MND Research
The battle against Motor Neuron Disease (MND) is entering an exciting phase with the development of gene therapies aimed at reducing pathogenic proteins. Read more
 Supervisors: Assoc Prof AL Lee, Assoc Prof MM Morsch
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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What is the relevance of hormones made in the brain?

University of Reading Department of Biomedical Sciences
Project Overview: . Read more
 Supervisors: Dr N Vasudevan, Prof P G Knight
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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