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We have 41 Pathology (clinical) PhD Projects, Programmes & Scholarships

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Pathology (clinical) PhD Projects, Programmes & Scholarships

We have 41 Pathology (clinical) PhD Projects, Programmes & Scholarships

Translating biomarkers towards clinical trial application in osteoarthritis

Stipend. Standard Research Council London Rate + Tuition Fees (Home rate) for 3 years. A consumables budget is also provided. Applications are invited for a 3-year PhD studentship based in the Centre for Inflammatory Disease, Department of Immunology & Inflammation at Imperial College London. Read more

The role of selective and novel biomarkers and their correlation with clinical outcome measures, pre and post-surgical treatment of benign and malignant disorders of the prostate

The Maelor Academic Unit of Medical & Surgical Sciences (MAUMSS) is a novel initiative by the Betsi Cadwaladr University Health Board (BCUHB), and is designed to encourage and support research within the Health Board and to promote academic activity, basic science and clinical research across North Wales (UK) and beyond. Read more

NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

Historically, articular cartilage was considered incapable of spontaneous repair.  However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more

NIHR Leeds BRC: Multimodal predictive modelling of outcome in patients with gastrointestinal cancer

Worldwide, cancer of the upper (oesophagus, stomach) and lower gastrointestinal (colon and rectum) tract is newly diagnosed in 3.6 million patients every year and 2.2 million patients die from this disease every year. Read more

Identifying DNA methylation signatures of prostate cancer progression and mortality among patients with clinically confirmed, localised disease at baseline in a large prospective clinical trial

Rationale. Prostate Cancer (PCa) is a leading cause of male mortality, with 336,000 deaths worldwide each year (1). Although most PCa cases are indolent, slow-growing, and tend not to progress, a subset of PCa cases are more aggressive and will progress to metastases, treatment resistance and death. Read more

MRes in Clinical Science

Our MRes Clinical Science is your chance to experience the reality of cutting-edge clinical or biomedical research. You’ll develop a broader, more considered approach to a specific area of medical research, gaining expertise in the intellectual and practical skills of scientific research in the process. Read more

Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

NIHR Leeds BRC: Force sensing mechanisms of haemostasis in heart failure and diabetes

Since the original identification of the role of PIEZO1 in vascular integrity and endothelial cell biology by our group in Leeds in 2014, there have been many publications on the role of PIEZO1 in endothelial function and its role in processes such as atherosclerosis, hypertension, cell-cell junctions, vascular permeability and leukocyte diapedesis. Read more

Clinical Significance and Diagnostic Accuracy of Special Tests in Rotator Cuff Related Shoulder Pain

Special tests are typically used to assist in the diagnostic process by implicating specific tissue structures that are either dysfunctional, pathological, or lack structural integrity, confirming the findings from the physical assessment and providing a tentative diagnosis (Magee, 2014). Read more

Alterations in reparative dentinogenesis with ageing, gender and genetic predisposition

Dental pulp exposure caused by tooth decay or injury can lead to life-threatening infections. Following injury, reparative dentinogenesis serves a vital purpose through the accelerated generation of tertiary dentine, comprising mineral and type I collagen. Read more

Antisense technologies as potential treatments for Cushing’s disease

Cushing’s disease is a devastating condition caused by a pituitary corticotroph tumour that over-expresses the proopiomelanocortin gene (POMC) and secretes high levels of ACTH. Read more

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