Pathology (funding) PhD Projects, Programmes & Scholarships

We have 76 Pathology (funding) PhD Projects, Programmes & Scholarships

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Supervisors: Dr M Hussain, Dr C Willis, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Supervisors: Dr M Hussain, Dr M Katsikogianni, Dr N Javid

Year round applications PhD Research Project Self-Funded PhD Students Only

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Beat-to-beat modulation of Calcium-induced Calcium release in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Contraction in the heart is well known to be dependent on a transient rise in intracellular calcium concentration. Read more

Supervisors: Dr M Hussain, Dr J Muller, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of the extracellular matrix as a regulator of Parkinson’s progression

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Parkinson’s is the 2nd most common neurodegenerative disease, affecting around 1 in 20 people aged over 65. In the UK, the number of affected people is set to rise by 50% over the next 50 years due to ageing populations. Read more

Supervisor: Dr SM Dickens

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanism of vimentin induced epithelial mesenchymal transition (EMT) and stemness in cancer cells

Queen Mary University of London Institute of Dentistry

Background. Most cancers are epithelial in origin and arise from a single progenitor cell, similar to an embryo, to become a clone of cells. Read more

Supervisors: Prof A Waseem, Dr H Tummala, Dr F Flores-Borja

Year round applications PhD Research Project Self-Funded PhD Students Only

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Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry

Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more

Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Skeletal Muscle Organoid Models for Genetic Mitochondrial Disease (ref: SF22/HLS/APP/Johnson)

Northumbria University Faculty of Health and Life Sciences

Genetic mitochondrial diseases are both clinically and genetically heterogeneous. Read more

Supervisor: Dr S Johnson

Year round applications PhD Research Project Self-Funded PhD Students Only

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What is the relevance of hormones made in the brain?

University of Reading Department of Biomedical Sciences

Project Overview: . Read more

Supervisors: Dr N Vasudevan, Prof P G Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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How do hormones regulate memory?

University of Reading Department of Biomedical Sciences

Deficiencies of thyroid hormone are common throughout the globe. Adult-onset hypothyroidism is prevalent in around 8-10% of the population and is associated with reproductive disorders, anxiety, depression and impairment of memory. Read more

Supervisors: Dr N Vasudevan, Prof P G Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the molecular mechanisms of thrombosis and haemostasis

University of Reading Department of Biomedical Sciences

Project Overview: . The risk of heart attack or stroke is elevated in obesity and in people with metabolic disorders such as diabetes. Read more

Supervisors: Dr C.E. Hughes, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

University of Leeds Faculty of Medicine and Health

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

Supervisors: Prof L Houghton, Dr D Peckham

Year round applications PhD Research Project Self-Funded PhD Students Only

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Low density lipoprotein oxidation and atherosclerosis

University of Reading Department of Biomedical Sciences

Project overview. The research in Professor David Leake’s group is concerned with atherosclerosis, the underlying cause of coronary heart disease and thrombotic strokes. Read more

Supervisor: Prof D S Leake

Year round applications PhD Research Project Self-Funded PhD Students Only

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Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

University of Reading Department of Biomedical Sciences

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Supervisor: Dr S Boateng

Year round applications PhD Research Project Self-Funded PhD Students Only

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Multi-organ signalling and diseases. How maintaining skeletal muscle mass impacts the development of liver diseases

University of Reading Department of Biomedical Sciences

Skeletal muscle has a number of roles in the human body beyond locomotion. It has a vital role in controlling the metabolic activity the organism. Read more

Supervisor: Prof K Patel

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 76 Pathology (funding) PhD Projects, Programmes & Scholarships

Pathology (funding) PhD Projects, Programmes & Scholarships

We have 76 Pathology (funding) PhD Projects, Programmes & Scholarships

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