Pathology (heart) PhD Projects, Programmes & Scholarships

We have 13 Pathology (heart) PhD Projects, Programmes & Scholarships

Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

University of Reading Department of Biomedical Sciences

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Supervisor: Dr S Boateng

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Supervisors: Dr M Hussain, Dr C Willis, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exploring cardio-renal-metabolic interactions in patients with heart failure

University of Dundee School of Medicine

Recent years have highlighted the connections and shared pathophysiology between heart failure, renal impairment, diabetes and obesity, particularly with the evidence of benefit in all of these areas with SGLT2 inhibitors and GLP1-receptor agonists. Read more

Supervisor: Dr I Mordi

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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NIHR Leeds BRC: Force sensing mechanisms of haemostasis in heart failure and diabetes

University of Leeds Faculty of Medicine and Health

Since the original identification of the role of PIEZO1 in vascular integrity and endothelial cell biology by our group in Leeds in 2014, there have been many publications on the role of PIEZO1 in endothelial function and its role in processes such as atherosclerosis, hypertension, cell-cell junctions, vascular permeability and leukocyte diapedesis. Read more

Supervisors: Dr R Ariens, Prof D J Beech, Dr E Levelt

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigation of short-term effects of colchicine on blood proteins using proteomics

University of Dundee School of Medicine

The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more

Supervisors: Prof G Rena, Dr I Mordi, Prof C Lang

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

Supervisors: Dr MM Mennon, Prof MH Buch

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

University of Dundee School of Medicine

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Supervisors: Dr L Kang, Dr C Murdoch

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Beat-to-beat modulation of Calcium-induced Calcium release in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Contraction in the heart is well known to be dependent on a transient rise in intracellular calcium concentration. Read more

Supervisors: Dr M Hussain, Dr J Muller, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genotypic and phenotypic markers of resistance in Aspergillus fumigatus and their impact on outcomes in chronic pulmonary aspergillosis

The University of Manchester Faculty of Biology, Medicine and Health

Chronic pulmonary aspergillosis (CPA) is a progressive infection affecting patients with chronic lung disease. It significantly affects quality of life and mortality. Read more

Supervisors: Dr CK Kosmidis, Dr M Bromley, Dr R Richardson, Dr M Bottery, Prof T Hussell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of ethnicity and inflammation in intramural hematoma to understand disease progression and guide future treatment avenues

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Intramural hematoma (IMH) is a life-threatening aortic disease. It involves bleeding within the medial layer of the aortic wall. Read more

Supervisors: Dr J Madine, Dr HL Wright, Dr R Akhtar, Mr M Field, Dr VS Sorokin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the molecular mechanisms of thrombosis and haemostasis

University of Reading Department of Biomedical Sciences

Project Overview: . The risk of heart attack or stroke is elevated in obesity and in people with metabolic disorders such as diabetes. Read more

Supervisors: Dr C.E. Hughes, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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Low density lipoprotein oxidation and atherosclerosis

University of Reading Department of Biomedical Sciences

Project overview. The research in Professor David Leake’s group is concerned with atherosclerosis, the underlying cause of coronary heart disease and thrombotic strokes. Read more

Supervisor: Prof D S Leake

Year round applications PhD Research Project Self-Funded PhD Students Only

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The regulation of platelet function - towards new strategies to prevent thrombosis

University of Reading Department of Biomedical Sciences

Project Overview. Platelets perform a pivotal role in the regulation of haemostasis, a physiological response to injury that prevents excessive bleeding. Read more

Supervisor: Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 13 Pathology (heart) PhD Projects, Programmes & Scholarships

Pathology (heart) PhD Projects, Programmes & Scholarships

We have 13 Pathology (heart) PhD Projects, Programmes & Scholarships

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