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Pathology (human) PhD Projects, Programs & Scholarships

We have 55 Pathology (human) PhD Projects, Programs & Scholarships

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  Molecular characterisation of novel interactions of DNA repair proteins
  Dr A Povey, Prof G Margison
Applications accepted all year round

Funding Type

PhD Type

Human exposure to alkylating agents is unavoidable through both exogenous sources and endogenous formation. Some of these compounds have been shown to be toxic and carcinogenic in animal models and some are known human carcinogens.
  Watching the Hippo pathway in real time in growing organs
  Dr K. Harvey
Applications accepted all year round

Funding Type

PhD Type

A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have drawn conclusions about gene function using indirect techniques that only allow us to infer what a gene normally does, without actually watching it work.
  Understanding differential responses to retinoid treatments in human health and disease: a precision medicine approach
  Prof R Watson, Dr A Langton
Applications accepted all year round

Funding Type

PhD Type

Retinoids, such as all-trans retinoic acid (t-RA), are endogenous signalling molecules derived from vitamin A that influence a variety of cellular processes through mediation of transcription events in the cell nucleus.
  Our Mission: to Educate, Nurture and Discover for the benefit of Human Health

Funding Type

PhD Type

Our ultimate purpose is to work in service of patients. RCSI was founded by Royal Charter on 11th February 1784, to set and support professional standards for surgical training and practice in Ireland.
  Predicting the development of oral cancer
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Human head and neck cancer is a devastating disease with poor survival rates.
  Potential therapeutic effects of natural products in Human Papillomavirus (HPV) related cervical cancers
  Dr H Ashrafi
Applications accepted all year round

Funding Type

PhD Type

Cervical cancer is one of the most common types of cancer affecting women worldwide. Infection caused by high-risk human papillomaviruses (HPVs), especially type 16 and 18 are implicated in the etiology of most cervical cancers.
  How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Amelogenesis is the process of enamel formation and is essential for the development of functional teeth. Amelogenesis imperfecta (AI) is a failure of that process.
  Examining Histoplasmosis in household and community environments at the human-animal interface
  Dr C Scantlebury, Prof A J McCarthy, Dr G Pinchbeck, Dr D Wooton
Applications accepted all year round

Funding Type

PhD Type

Little is known about the current prevalence or transmission of Histoplasmosis despite its persistence in Sub-Saharan Africa, representing a public health blind spot (Oladele et al., 2018).
  Endothelial senescence and healthy ageing
  Prof S Francis, Prof I Bellantuono
Applications accepted all year round

Funding Type

PhD Type

Endothelial senescence is a key biological mechanism in the development of coronary artery disease and ageing.
  Development of a three dimensional in vitro model of the human cornea to dissect the inflammatory events associated with sight-threatening ocular pathogens
  Dr C Dobson, Dr C Maldonado-Codina, Prof P Morgan
Applications accepted all year round

Funding Type

PhD Type

The presence of microbes at the corneal surface may trigger low grade discomfort through to acute eye infection and permanent loss of vision.
  Insights into eye disease: understanding the molecular basis of age-related macular degeneration
  Prof T Day, Dr S Clark
Applications accepted all year round

Funding Type

PhD Type

Dysregulation of innate immunity has been implicated as playing a key role in the development of age-related macular degeneration (AMD) – a major form of blindness in the industrialised world (see [1-5]).
  Characterisation of in vitro models of human salivary glands and their use in functional studies
  Dr L Bingle, Prof C Bingle
Applications accepted all year round

Funding Type

PhD Type

Saliva is produced by three pairs of major salivary glands and multiple minor glands in the lips, associated with the tongue and also with the palate.
  Homeostatic mechanisms in human urothelium: balancing of tissue regeneration and differentiation with implications for regenerative medicine and cancer
  Prof J Southgate
Application Deadline: 30 June 2020

Funding Type

PhD Type

The urothelium is the self-regenerating epithelium that lines the bladder, where it is highly specialised to function as a urinary barrier.
  Investigating the requirements of pro-inflammatory signaling in skin and head & neck Squamous Cell Carcinomas
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Squamous cell carcinomas (SCC) are amongst the most common cancer types afflicting man. SCCs most frequently arise from stratified squamous epithelia such as the epidermis or the mucosae of the head and neck.
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
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