Pathology (in vitro) PhD Projects, Programmes & Scholarships

We have 15 Pathology (in vitro) PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

Supervisors: Dr MM Mennon, Prof MH Buch

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Using pre-clinical models of disease to define new targets to slow joint degeneration in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences

The main overall aim of this project is to understand mechanisms of joint degeneration during osteoarthritis progression in order to define new targets for therapy. Read more

Supervisor: Dr B Poulet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Study of early pathological changes in calcified cartilage in osteoarthritis and alkaptonuria

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

We are seeking a motivated individual to work on this exciting project investigating the role that the calcified cartilage has in rare and common joint osteoarthritis, using novel approaches such as gene silencing and establishment of a 3D chondrocyte cell culture model. Read more

Supervisor: Dr JH Hughes

10 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Supervisors: Dr M Secrier, Dr L Cottone

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Unravelling the Intricacies of Stress Hormone Regulation

University of Reading Department of Biomedical Sciences

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Supervisor: Dr A B Bicknell

Year round applications PhD Research Project Self-Funded PhD Students Only

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NIHR Leeds BRC: Force sensing mechanisms of haemostasis in heart failure and diabetes

University of Leeds Faculty of Medicine and Health

Since the original identification of the role of PIEZO1 in vascular integrity and endothelial cell biology by our group in Leeds in 2014, there have been many publications on the role of PIEZO1 in endothelial function and its role in processes such as atherosclerosis, hypertension, cell-cell junctions, vascular permeability and leukocyte diapedesis. Read more

Supervisors: Dr R Ariens, Prof D J Beech, Dr E Levelt

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Preventing Prostate Cancer, and Related Metastases

Medical University of Vienna Institute for Pathophysiologie and Allergy

The goal of this project is to elucidate the role of the thyroid hormone pathway for prognosis and therapy response of prostate cancer (PCa). Read more

Supervisor: Dr L Kenner

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Fertility preservation of male childhood cancer patients

University of Dundee School of Medicine

Every day, around five children receive a diagnosis of cancer in the United Kingdom, with boys slightly more frequently than girls. Read more

Supervisors: Dr F Lopes, Prof R Mitchell

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Free Circulating Histone Variants and Their Complexes in Biofluids as Novel Markers of Diseases

Masaryk University Faculty of Medicine

Affiliation. Masaryk University, Faculty of Medicine. Study program. PhD program Biomedical Sciences. Specialization. Biochemistry and Molecular Biology. Read more

Supervisor: Dr JF Fröhlich

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle

Year round applications PhD Research Project Self-Funded PhD Students Only

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Ejecting infection: Understanding how epithelial tissues rid themselves of viral infections by apical extrusion

University of York York Biomedical Research Institute

Background. The epithelial tissues of our bodies use physical barriers and innate defences to fight viral infection. Read more

Supervisor: Dr S Baker

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of new molecular therapies to treat motor neuron disease (MND)

Macquarie University Centre for MND Research

The battle against Motor Neuron Disease (MND) is entering an exciting phase with the development of gene therapies aimed at reducing pathogenic proteins. Read more

Supervisors: Assoc Prof AL Lee, Assoc Prof MM Morsch

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Vascularisation of tumour organoids for mechanistic and drug development

University of Dundee School of Medicine

Gliomas such as are the most common form of brain tumour, a subset Glioblastoma (GBM) are devastating adult brain cancer with high rates of recurrence and treatment resistance. Read more

Supervisors: Dr C Murdoch, Dr S Banerjee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Improvements of asparaginase-based treatment for Childhood ALL

Cardiff University Cardiff School of Biosciences

Project Description. Most popular current treatments for childhood acute lymphoblastic leukaemia (ALL) in clinic are based on asparaginase (Raja et al 2012). Read more

Supervisors: Dr O V Gerasimenko, Dr J Gerasimenko

Year round applications PhD Research Project Self-Funded PhD Students Only

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Creation of cell lines modelling complex karyotype in B cell lymphomas using CRISPR/Cas9

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Chronic lymphocytic leukaemia (CLL) and diffuse large B cell lymphoma (DLBCL) make up more than half of all the newly diagnosed cases of non-Hodgkin’s lymphoma (NHL), the 6th most common cancer in the UK. Read more

Supervisors: Dr J Slupsky, Dr N Kalakonda, Dr M Glenn

1 May 2024 PhD Research Project Self-Funded PhD Students Only

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We have 15 Pathology (in vitro) PhD Projects, Programmes & Scholarships

Pathology (in vitro) PhD Projects, Programmes & Scholarships

We have 15 Pathology (in vitro) PhD Projects, Programmes & Scholarships

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