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Pathology (infection biology) PhD Projects, Programs & Scholarships

We have 16 Pathology (infection biology) PhD Projects, Programs & Scholarships

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  Ph.D. Fellowship in Intestinal Innate Immunity and Host Defense Peptides
  Dr E Cobo
Applications accepted all year round

Funding Type

PhD Type

RESEARCH. One Ph.D. position is available immediately at the University of Calgary, Canada to study gut innate immunity contributed by host defense peptides and immunoregulation in the epithelial and leukocyte cross-talking in response to microbial pathogens.
  How does nutritional status affect plant immunity and disease?
  Dr R Harrison, Prof J M Dunwell
Application Deadline: 28 February 2020

Funding Type

PhD Type

REFERENCE. CTP_FCR_2020_3. Supervisors. Dr Richard Harrison (NIAB EMR), Prof Jim Dunwell (University of Reading). This student will be registered with the University of Reading.
  Investigating the impact of chronic parasite infection on immune cell development
  Dr J Hewitson, Prof I Hitchcock
Application Deadline: 30 June 2020

Funding Type

PhD Type

More than a quarter of the global population is infected with a parasitic worm, resulting in a range of diseases and pathologies.
  Targeting pathogen subversion of cellular ageing to combat antimicrobial-resistant typhoid fever
  Dr D Humphreys, Dr T Darton
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial-resistant typhoid fever is fuelled by chronic Salmonella carriage. The world faces epidemics of untreatable typhoid fever caused by antimicrobial-resistant strains of Salmonella Typhi (~27 million cases/year).
  Adaptation to oxidative stress in hepatitis C virus persistence: the role of IRES-dependent translation.
  Dr S-W Chan, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

Hepatitis C virus (HCV) causes a clinically important disease affecting 3% of the world population (Chan 2014). About 75% of the infection will develop into chronic hepatitis, which can then progress into fibrosis, cirrhosis and hepatocellular carcinoma.
  (WIS) Cross-talk between T cells and intestinal epithelial cells: a new type of immune synapse.
  Prof D Davis, Prof M Travis
Application Deadline: 6 March 2020

Funding Type

PhD Type

Super-resolution and other state-of-the-art microscope techniques allow us to study immune cell activity in unprecedented detail.
  Predicting the development of oral cancer
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Human head and neck cancer is a devastating disease with poor survival rates.
  Development of a three dimensional in vitro model of the human cornea to dissect the inflammatory events associated with sight-threatening ocular pathogens
  Dr C Dobson, Dr C Maldonado-Codina, Prof P Morgan
Applications accepted all year round

Funding Type

PhD Type

The presence of microbes at the corneal surface may trigger low grade discomfort through to acute eye infection and permanent loss of vision.
  Characterising broad-acting resistance to bacterial canker of cherry and elucidating tissue-specific mechanisms of immunity
  Dr M Hulin, Dr R Harrison, Dr G Barrett, Prof J M Dunwell
Application Deadline: 28 February 2020

Funding Type

PhD Type

REFERENCE. CTP_FCR_2020_4. Supervisors. Dr Michelle Hulin (NIAB EMR), Dr Richard Harrison (NIAB EMR), Prof John Mansfield, Dr Glyn Barrett (University of Reading).
  Engineering tolerance to Botrytis in soft fruit crops
  Dr C Nellist, Dr H Cockerton, Prof M Dickinson, Dr T P Robbins
Application Deadline: 28 February 2020

Funding Type

PhD Type

REFERENCE. CTP_FCR_2020_11. Supervisors. Dr Charlotte Nellist (NIAB EMR), Dr Helen Cockerton (NIAB EMR), Prof Matthew Dickinson (University of Nottingham), and Dr Tim Robbins (University of Nottingham).
  Basal stem cells in the lung and their recognition of dying cells
  Prof T Hussell, Dr N Fujino
Applications accepted all year round

Funding Type

PhD Type

Stem cell division and differentiation is critical for barrier repair following inflammation, but the initial trigger for this process is unknown.
  Virus pathogenesis: interplay between the unfolded protein response and innate immunity.
  Dr S-W Chan, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

The unfolded protein response (UPR) is a cellular homeostatic response in restoring endoplasmic reticulum balance upon stress conditions e.g.
  How does cytokine signalling cause kidney hyperplasia?
  Dr M Fragiadaki, Prof J Sayers
Applications accepted all year round

Funding Type

PhD Type

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney disorder, with more than 12 million people are affected worldwide.
  Potential therapeutic effects of natural products in Human Papillomavirus (HPV) related cervical cancers
  Dr H Ashrafi
Applications accepted all year round

Funding Type

PhD Type

Cervical cancer is one of the most common types of cancer affecting women worldwide. Infection caused by high-risk human papillomaviruses (HPVs), especially type 16 and 18 are implicated in the etiology of most cervical cancers.
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
  Budding yeast as a model for sudden cardiac death
  Dr T Hoefken
Applications accepted all year round

Funding Type

PhD Type

Sudden unexpected cardiac death is responsible for about half of all heart disease deaths. It is an unexpected death caused by a change in heart rhythm.
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