We have 92 Pathology PhD Projects, Programmes & Scholarships for Self-funded Students

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Pathology PhD Projects, Programmes & Scholarships for Self-funded Students

We have 92 Pathology PhD Projects, Programmes & Scholarships for Self-funded Students

Unravelling the Intricacies of Stress Hormone Regulation

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Normative modelling of resting-state EEG across the lifespan for application in the early diagnosis of neurodegenerative disorders including Alzheimer’s disease

With a rapidly aging human population worldwide, neurodegenerative diseases represent a pressing medical and societal concern. Given the increase in life expectancy, dementia is expected to affect almost 152 million people by 2050 (Alzheimer’s Disease International, 2018). Read more

Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more

Illuminating tissue barriers leading to treatment resistance and bowel cancer recurrence

Colorectal cancers are typically treated by chemotherapy, radiotherapy, and surgical removal. However, despite treatment, up to 50% of patients develop recurrence of disease – that is, the cancer returns either close to the original site or having spread to other places in the body. Read more

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Virus-like particles as a drug-delivery platform

Targeted delivery of therapeutics – ensuring that the correct cells receive the correct molecules at the correct time is key to lessening the side effects associated with many major therapies. Read more

Repositioning blood pressure lowering drugs to treat Alzheimer’s disease

Elevated blood pressure in mid-life is a risk factor for Alzheimer’s disease (AD). Blood pressure lowering drugs protect against cognitive decline and may slow the progression of AD. Read more

Drug-Coated Balloon Therapy in Coronary Artery Disease Management

Applications are invited for a Postgraduate studentship, supported by Sandwell and West Birmingham NHS Trust to be undertaken within the College of Health and Life Sciences at Aston University. . Read more

National Institute for Health Research School for Primary Care Research PhD studentship

Applications are invited for NIHR School for a Primary Care Research studentship in primary health care from individuals with a strong academic record who wish to develop a career in primary care research. Read more

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