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Pathology (genomic) PhD Projects, Programmes & Scholarships
We have 7 Pathology (genomic) PhD Projects, Programmes & Scholarships
We have 7 Pathology (genomic) PhD Projects, Programmes & Scholarships
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A Multi-Omics approach to understanding cardiovascular risk in patients with End-Stage Kidney Disease
Background. End-stage Kidney failure, also known as End-Stage Kidney Disease (ESKD), is the final, irreversible stage of chronic kidney disease (CKD), where kidney function has worsened to the point that the kidneys can no longer function independently. Read more
De Novo Mutations and Human Disease
De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most originate, the human testis. Read more
De Novo Mutations and Human Disease
De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most originate, the human testis. Read more
Breaking bad: Evolution by loss-of-function
Paradoxically, the first step adaptation to a new environment often involves losing genes, rather than gaining new ones—a phenomenon observed across the tree of life. Read more
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The molecular basis of glial cell heterogeneity in human brain
Glial cells constitute a large fraction of the mammalian brain. Although initially considered as non-functional supporter for neuron function, recent studies have revealed that glial cells have critical roles in the brain under both physiological and pathological conditions. Read more
Epigenetic regulation in heart failure and cardiac sudden death
A large proportion of heart failure patients die from cardiac sudden death (SCD), a direct result of lethal ventricular arrhythmias, which is the principal cause of mortality from heart disease worldwide and remains a major unresolved public health problem. Read more
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