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University of Oxford Pathology PhD Projects, Programs & Scholarships

We have 41 University of Oxford Pathology PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 41
  Understanding Neuroinflammation through advanced in vitro 3D modelling using human Pluripotent Stem Cells
  Dr S Cowley, Prof W S James
Application Deadline: 25 January 2019
Microglia - brain-resident macrophages - carry out homeostatic surveillance functions in the brain, clearing dying cells, extracellular debris, and pruning synapses during development.
  Targeting TFEB to correct autophagy/lysosomal deficits in Parkinson’s disease
  Prof R Wade-Martins
Application Deadline: 11 January 2019
Commercial partner. Biogen, Cambridge, Massachusetts, USA. Parkinson’s disease is the second most common neurodegenerative disorder but disease-modifying therapies are still lacking.
  A novel arterial macrophage subset in atherosclerosis
  Prof C Monaco, Prof I Udalova
Application Deadline: 11 January 2019
Obesity, insulin resistance, type 2 diabetes (T2D), and associated cardiovascular disease (CVD) often coexist clinically and constitute an epidemic global health problem.
  Characterising Key Determinants of Fibroblast Function in Immune Mediated Inflammatory Disease
  Prof C Buckley, Prof M Coles
Application Deadline: 11 January 2019
Immune mediated inflammatory diseases (IMIDs) including Rheumatoid arthritis (RA), inflammatory bowel disease and Sjogren’s syndrome result from interactions between innate and adaptive immune cells with stromal fibroblasts driving both inflammation and tissue damage.
  How does immunometabolism vary in time and space in the germinal centre?
  Dr A Clarke, Prof R Cornall
Application Deadline: 11 January 2019
The germinal centre (GC) reaction is responsible for the production of high-affinity antibodies and immune memory. It is vital for an effective humoral immune response, for example following vaccination.
  Interrogating the role of vascular microenvironments during T cell development
  Dr A Kusumbe, Prof M Dustin
Application Deadline: 11 January 2019
The Project. The thymic microenvironment harbours a hierarchical system of lymphoid/T cell progenitors and supports T cell development which is crucial forgeneration of adaptive immune diversity.
  Investigating the causes of inflammatory arthritis with computational and single-cell genomics
  Dr S Sansom, Prof P Bowness
Application Deadline: 11 January 2019
Ankylosing spondylitis (AS) is a common and highly heritable1form of arthritis which characteristically involves inflammation of the sacroiliac joints and spine.
  Is there a unique stool and blood inflammatory signature in Ankylosing Spondylitis?
  Prof P Bowness, Prof F Powrie
Application Deadline: 11 January 2019
Ankylosing Spondylitis (AS) is a common inflammatory rheumatic disease of unknown pathogenesis.
  Priming of the NLRP3 inflammasome in sterile inflammation
  Dr J Mirkovic, Prof K Midwood
Application Deadline: 11 January 2019
At the front line of immune defence lies the innate immune system, a component of which is the NLRP3 inflammasome—a multi-molecular sensing and signalling platform that recognizes the presence of infection or damaged tissue.
  Regional humoral immunity in the lung; exploring the function and biology of resident memory B cells in resistance against influenza virus
  Dr T Arnon, Prof I Udalova
Application Deadline: 11 January 2019
Influenza virus is a common airborne pathogen that continues to present a significant medical challenge causing over 3 million cases of critical illness and up to 500,000 deaths per annum.
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