or
Continue with FacebookLooking to list your PhD opportunities? Log in here.
We have 9 Pharmaceutical Chemistry (business and finance) PhD Projects, Programmes & Scholarships
Pharmaceutical Chemistry (business and finance) PhD Projects, Programmes & Scholarships
We have 9 Pharmaceutical Chemistry (business and finance) PhD Projects, Programmes & Scholarships
Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents
Research Group:
Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy
Research Group:
Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more
Investigation of novel PARP7-targeting agents for the treatment of cancer
PARP7, an ADP-ribosyltransferase, modulates protein function by adding an ADP-ribose moiety to target proteins. It is involved in many physiological and pathophysiological processes such as neural development, maintenance of stem cells, immunity, xenobiotic metabolism, immunity and cancers. Read more
Determination of therapeutic potential of different formulations of curcumin as an effective treatment option for pulmonary hypertension
Pulmonary hypertension (PAH) is debilitating condition characterized by thick and stiff blood vessels that are unable to expand resulting in an increased pressure in the blood vessels supplying the lungs. Read more
Development and characterisation of cortical organoid model for drug discovery to treat cognitive impairment in schizophrenia
Schizophrenia is a psychiatric disorder which severely impairs the individual’s ability to function in society. The most recognised symptoms are delusions and hallucinations, but patients also suffer from memory and attention problems. Read more
Evaluation of human pluripotent stem cell-derived cardiac myocytes for cardiotoxicity testing
Research Group:
Chemistry and Biosciences
Evaluation of human-induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CMs) for cardiotoxicity testing Potentially fatal cardiac arrhythmias such as Torsades des Pointes (TdP) are linked to adverse side-effects of drugs intended as potential treatments for a variety of clinical disorders. Read more
Formulation and biopharmaceutical characterisation of novel pro-antibiotics for improved oral permeability
Research Group:
Pharmacology and Experimental Therapeutics
This project is focused on the formulation, synthesis, and biopharmaceutical characterisation of novel pro-antibiotics for improved oral bioavailability. . Read more
Computational and machine learning driven development of new polysialyltransferase (ST8SiaII) inhibitors against metastatic cancer
Research Group:
Institute of Cancer Therapeutics
Polysialic acid (polySia) is a carbohydrate polymer important for embryonic development. PolySia is absent in healthy adult tissues whereas overexpressed in several tumours. Read more
Formulation of heterogenous solid dispersions produced by spray drying and hot-melt extrusion for improved delivery of amorphous drugs
Research Group:
Pharmacology and Experimental Therapeutics
Production of the amorphous solid dispersions (ASDs) is a one of the methods of improving of physicochemical properties of an active pharmaceutical ingredient (API) such as its solubility and physicochemical stability. Read more
- 1