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We have 6 Pharmaceutical Chemistry (business process) PhD Projects, Programmes & Scholarships
Pharmaceutical Chemistry (business process) PhD Projects, Programmes & Scholarships
We have 6 Pharmaceutical Chemistry (business process) PhD Projects, Programmes & Scholarships
Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy
Research Group:
Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more
Formulation and biopharmaceutical characterisation of novel pro-antibiotics for improved oral permeability
Research Group:
Pharmacology and Experimental Therapeutics
This project is focused on the formulation, synthesis, and biopharmaceutical characterisation of novel pro-antibiotics for improved oral bioavailability. . Read more
Computational and machine learning driven development of new polysialyltransferase (ST8SiaII) inhibitors against metastatic cancer
Research Group:
Institute of Cancer Therapeutics
Polysialic acid (polySia) is a carbohydrate polymer important for embryonic development. PolySia is absent in healthy adult tissues whereas overexpressed in several tumours. Read more
Formulation of heterogenous solid dispersions produced by spray drying and hot-melt extrusion for improved delivery of amorphous drugs
Research Group:
Pharmacology and Experimental Therapeutics
Production of the amorphous solid dispersions (ASDs) is a one of the methods of improving of physicochemical properties of an active pharmaceutical ingredient (API) such as its solubility and physicochemical stability. Read more
New Drugs for Brain Tumours: Prodrugs of Diazopropyne
Research Group:
Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more
New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics
Research Group:
Medicines Development and Pharmaceutical Sciences
The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more
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