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Pharmaceutical Chemistry (metabolism) PhD Projects, Programmes & Scholarships

We have 6 Pharmaceutical Chemistry (metabolism) PhD Projects, Programmes & Scholarships

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We have 6 Pharmaceutical Chemistry (metabolism) PhD Projects, Programmes & Scholarships

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Metabolism, Stress and the Cell Cycle in Human Hair Follicle Growth and Inflammation

The human hair follicle is a highly proliferative tissue system with unique and complex energy needs to grow hair. This PhD project will examine the links between metabolism and proliferation in human hair follicles, including within epithelial stem and progenitor cell populations. Read more

Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact

Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more

Self Funded PhD Project: Studies on the Design, Synthesis and Biological Evaluation of a Novel Bioactive Indane Scaffold

A wide range of bioactive indane based scaffolds are employed clinically as treatment of many disease states, including inflammatory [1], cancer [2] and neurological conditions [3] and also in the treatment of HIV [4]. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
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