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Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships

We have 116 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships

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We have 116 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships

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Stabilizers of the interaction between 14-3-3 and hDM2/hDMX

  Research Group: School of Chemistry
Transient protein-protein interactions (PPIs) control all cellular processes relevant to health and disease. Selective modulation of individual PPIs would thus facilitate both a greater understanding of biological mechanisms and provide new opportunities for therapeutic intervention. Read more

Development of Novel Bioconjugation Approaches

Recent efforts in our group have sought to selectively exploit the reactivity of a transient intermediate generated from a stable precursor for applications in synthesis, medicinal chemistry, and chemical biology. Read more

Discovery of novel cancer immunotherapeutic agents

Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high mortality. Read more

Deep learning methods in multi-omics data analysis for critical disease

Personalised treatment is a new and strategic approach to separating patients into different groups based on their personal response or risk of disease so that treatments can be tailored to the individual patient. Read more

Digital twin in continuous UF/DF step of bioprocess

Continuous technology represents the future tendency of biopharmaceutical processing. Compared to the batch process, the continuous process has benefits of reduced cost, increased productivity, improved product quality and flexibility. Read more

Machine learning for decision making: how to choose the optimal strategy for stratified medicine life cycle

Stratified medicine is at the cutting edge of a new era in healthcare, which targets to a specific patient population on the basis of a companion diagnostic (such as a biomarker) to predict treatment efficacy or adverse side effects. Read more

Design of novel inhibitors of AIM-2 for the treatment of inflammation.

Inflammation is a contributing factor in a range of therapeutic areas including stroke, Alzheimer’s disease and cancer. A cause of Inflammation is through the activation of multi-protein complexes called inflammasomes, which facilitates the release of cytokines, including IL-1b. Read more

Probing Viral Receptor-Glycan Interactions using Polyvalent Multifunctional Glycan-Nanoparticle

  Research Group: School of Chemistry
Multivalent viral receptor-glycan interactions are central to viral infection and immune response regulation. However, the underpinning structural mechanisms are often poorly understood, due to a lack of effective probes for such complex, multimeric and flexible proteins. Read more

Cell-type dependent pharmacological regulation of cellular mitophagy for therapeutic application in Parkinson’s disease

The cellular quality-control process of mitophagy, entailing selective degradation of defective mitochondria (following damage to their DNA) by the process of autophagy, has attracted considerable research interest. Read more

Development of fluorescent sensors for biological application

We are looking for a highly motivated, passionate and competitive candidate to carry out PhD research in fluorescent sensing and chemical biology in an international team working on the development of chemical sensors for biological studies. Read more

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