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Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships

We have 116 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships

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We have 116 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships

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Advanced manufacturing of paediatric formulations with poorly water soluble drugs

This project employs an advanced manufacturing technique, microwave-induced in situ amorphization, in combination with a wide range of characterization techniques to tackle the consistent stability issue of amorphous solid dispersions as a means of improving the dissolution performance of paediatric personalised formulations with poorly water soluble drugs.   . Read more

Enhancing Protein and Ligand Sampling in Molecular Simulations by Fully Adaptive Simulated Tempering (FAST)

Supervisory Team.   Prof J.W. Essex, Dr Michael Bodnarchuk (AZ), Dr Ian Wall (GSK). Project description. Binding free energy calculations are a widely used technique in the pharmaceutical industry to identify molecules which may be usefully developed into drug candidates. Read more

Prediction of Manufacturability and Transformations During Amorphous Pharmaceuticals Processing

KEYWORDS. Pharmaceuticals, manufacture, polymers, materials science, modelling, 3D printing, extrusion, formulation. CMAC is a world leading medicines manufacturing research center that hosts a portfolio of collaborative research programs aimed to transform the development and manufacture of medicines (www.cmac.ac.uk). Read more

Optimising the washing and drying of filter cakes: modelling and applications

The aims of project are to understand fluid transport through filter cakes, and how it is influenced by particle sizes and cake structural properties; Investigate the consequences of this fundamental understanding for washing and drying, which are key processes in the manufacture of pharmaceuticals; and design improved strategies for isolation of particulates that facilitate further processing. Read more

Solvent reuse to support sustainable pharmaceutical manufacturing

This project aims to develop and demonstrate solvent recycling methodologies which can be applied within individual process stage during advanced continuous pharmaceutical synthesis and active pharmaceutical ingredient isolation. Read more

Predicting drug solubility in different solvents using molecular simulation and machine learning

Predicting the solubility of complex drug-like molecules is crucial at several stages of the drug discovery and manufacture. In particular, solvent selection has been highlighted as a crucial step in process design and optimisation [1]. Read more

Neuropeptide Research – PhD Position at a World Class Institution

Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases. Read more

Biochemical Optimisation of a Male Contraceptive

The development of a reversible and non-hormonal male contraceptive will supplement existing birth control options to achieve a significant impact upon the numbers of unwanted pregnancies, a major global problem. Read more

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