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We have 51 Pharmaceutical Chemistry (cell) PhD Projects, Programmes & Scholarships for Self-funded Students
Pharmaceutical Chemistry (cell) PhD Projects, Programmes & Scholarships for Self-funded Students
We have 51 Pharmaceutical Chemistry (cell) PhD Projects, Programmes & Scholarships for Self-funded Students
Single cell genomics to advance treatments for human adipose tissue dysfunction.
Obesity affects 1 billion people worldwide and is a leading cause of diabetes, heart disease, dementia and cancer1,2. Pathological adipose tissue expansion and remodeling (characterised by inflammation, metabolic dysfunction and fibrosis) is a major driver of the harmful health consequences of obesity3. Read more
Development of Organelle Targeted Ligands to Delineate GPCR signalling
G protein-coupled receptors (GPCRs) are a large family of integral membrane proteins comprising seven transmembrane α-helical domains that relay… Read more
Development of Organelle Targeted Ligands to Delineate GPCR signalling
G protein-coupled receptors (GPCRs) are a large family of integral membrane proteins comprising seven transmembrane α-helical domains that relay… Read more
Evaluation of human pluripotent stem cell-derived cardiac myocytes for cardiotoxicity testing
Research Group:
Chemistry and Biosciences
Evaluation of human-induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CMs) for cardiotoxicity testing Potentially fatal cardiac arrhythmias such as Torsades des Pointes (TdP) are linked to adverse side-effects of drugs intended as potential treatments for a variety of clinical disorders. Read more
New Polymer Biomaterials to Expand and Deliver Cells with Animal-Free Technologies
This PhD will seek to discover new polymeric biomaterials which can modulate stem-cell function, and aid in their delivery to either patients, or as cell factories. Read more
Developing anti-cancer drugs: Inhibiting Mortalin function to prevent cancer cell proliferation
These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more
MRes - Developing novel PROTAC molecules targeting mutated BRAF (V600E) in melanoma disease: design, synthesis, and biological evaluation Project ID (SAS0215).
Melanoma ranks as the fifth most common cancer in the UK with over 132,000 new cases reported annually worldwide. According to the World Health Organization, this figure is predicted to rise significantly, reaching 500,000 by 2040. Read more
Targeting glycans on the outside of cells, as new therapeutics
Most drugs have intracellular targets (proteins etc). This creates a barrier to how to target a cell, and then get the drug inside the cell. Read more
Drug Development for Parkinson's Disease
PhD Student Position. Drug Development for Parkinson's Disease. The Brodski Lab. Our lab investigates the molecular mechanisms controlling the development, survival, and degeneration of dopaminergic neurons, aiming to leverage our findings to develop novel therapies for dopamine-related disorders. Read more
Chemical Biology and Structure-based approaches to study novel induced-proximity modalities
Primary Supervisor: Dr Elena De Vita. Co-Supervisor(s): Dr Ben Stieglitz. Funding: China Scholarship Council (CSC). Read more
Understanding Autoimmune Diseases Using Mass Spectrometry
Research Group:
School of Chemistry
Glycans are sugar-based molecules which play an important role in biological processes ranging from cell-cell communication to energy metabolism. Read more
MRC DiMeN Doctoral Training Partnership: Enhancing LNP-RNA delivery to leukemia cells through cutting-edge cryogenic electron tomography (cryo-ET)
Lipid nanoparticles (LNPs) are one of the most exciting medical technologies developed over the last few decades. These synthetic structures allow nucleic acids, such as oligonucleotides or mRNA, to be hidden in their core and delivered to cells within the body. Read more
MRC DiMeN Doctoral Training Partnership: The role of phosphodiesterases (PDEs) in atrial IP3 signaling: Exploring the potential of utilizing PDEs as therapies for atrial fibrillation
Our project is aligned with MRC and DiMeN Strategy - to tackle major health problems and improve human health. Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia (incidence 1-2%). Read more
MRC DiMeN Doctoral Training Partnership: Developing Novel Anti-Inflammatory Agents for Age-Related Diseases
Join our interdisciplinary team supervised by Heather Wilson, Joseph Harrity & Gareth Richards, at the University of Sheffield to tackle a pressing challenge in modern medicine as part of the prestigious MRC Discovery Medicine North (DiMeN) Doctoral Training Partnership. Read more
Inhibitor of DONSON-GINS interaction as an experimental tool and potential anticancer strategy
Application deadline - midday (GMT) Friday 10 January 2025. Inhibition of initiation of DNA replication is an attractive and promising anticancer strategy. Read more