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Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships
We have 124 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships
We have 124 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships
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Development of fluorescent sensors for biological application
We are looking for a highly motivated, passionate and competitive candidate to carry out PhD research in fluorescent sensing and chemical biology in an international team working on the development of chemical sensors for biological studies. Read more
Modular Synthetic Platform for the Optimisation of Fragment Hits Using Bifunctional 3-D Building Blocks
Modular Synthetic Platform for the Optimisation of Fragment Hits Using Bifunctional 3-D Building Blocks. Supervisor. Peter O’Brien. Read more
Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2 – Towards New Antivirals for the Treatment of COVID-19
Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2 – Towards New Antivirals for the Treatment of COVID-19. Read more
Catalytic Asymmetric ‘Clip-Cycle’ Reactions: Synthesis of Heterocycles Important in Drug Discovery
Cyclic ethers and amines are ubiquitous in biologically active natural and non-natural products. However, despite this prevalence and importance, there is no strategy for their asymmetric synthesis which is independent of heteroatom and/or ring size. Read more
Designing inhibitors of protein-protein interactions for bacterial cell division for specific antibiotics (BEEKMANA_U23SF)
Antibiotic-resistant pathogens are a huge threat in healthcare. The last resorts of conventional antibiotic drugs are unable to treat multi-resistant strains in patients. Read more
Last chance to apply
PhD Studentship Opportunity: Blade spray mass spectrometry for characterisation and quantification of mutagenic impurities in pharmaceutical reaction mixtures
Blade spray mass spectrometry is a new and exciting development to characterise molecules rapidly, and accurately, at very low (sub parts per billion) levels in complex matrices. Read more
Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact
Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more
Last chance to apply
Investigation of Formulation Design Solutions for Low Global Warming Potential Pulmonary Drug Delivery Systems
Research Group:
Chemistry and Biosciences
In 1987 the Montreal Protocol defined a pathway to eliminate the compounds proven to be harmful for the ozone, such as chlorofluorocarbon (CFC) employed as propellants in pressurised metered dose inhalers (pMDIs). Read more
Last chance to apply
Medicinal Chemistry and Imaging Project: Novel Imaging, synthetic chemistry and applications of the Ion Beam Centre in the diagnosis of the asbestos induced lung cancer mesothelioma
The Project. Mesothelioma is a rare and fatal lung cancer, always associated with asbestos exposure. There is no current cure for mesothelioma and there are no reliable early detection methods. Read more
Last chance to apply
Novel Electrochemical and Photochemical C-H Activation Methods for Heterocycle Synthesis and applications in total synthesis
The Project. Saturated oxygen and nitrogen containing heterocycles are widespread across natural products and pharmaceutically active ingredients. Read more
Flexible Peptide Decorated Polyaminocarboxylate Ligands for Selective Extraction of Radiotherapeutic Metals for Targeted Alpha Cancer Therapy
Nuclear fission produces radioactive isotopes with decay products encompassing a large proportion of the Periodic Table. Many of these isotopes are considered as waste and are currently disposed of following separation. Read more
Epigenetic mechanisms and functional pathways linking maternal immune activation and cognitive impairment in a neurodevelopmental model for schizophrenia
A fundamental unknown in understanding disease mechanisms is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more
Developing nanoparticles to target neuroendocrine tumour for overcoming resistance to cancer treatment
Many cancer patients having undergone local and systemic treatment eventually develop and die from the progression of distant metastasis associated with the relapse in primary tumour growth. Read more
Development of peptide hydrogel as an anticancer drug carrier
Growth in nanotechnologies can now be exploited to enable engineering of new drug delivery systems for enhancing the entrapment of drugs in nano-sized structures with tailored physical properties to suit therapeutic need. Read more
Inorganic chaperones fused to fungal derived chemotherapeutic agents for the treatment of neuroblastoma
This is a unique and cutting-edge PhD research opportunity in the multidisciplinary field of nanotechnology for a student with a strong background in chemistry / biochemistry interested in applying knowledge and developing drugs and drug delivery systems for cancer chemotherapy. Read more