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We have 23 Pharmaceutical Chemistry (cell biology) PhD Projects, Programmes & Scholarships

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Pharmaceutical Chemistry (cell biology) PhD Projects, Programmes & Scholarships

We have 23 Pharmaceutical Chemistry (cell biology) PhD Projects, Programmes & Scholarships

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Does one size fit all for antimicrobial delivery via nanoparticles

Queen’s University Belfast School of Pharmacy
Antimicrobial resistant bacteria are a growing problem and new ways are needed to target bacterial infections more efficiently. One way in which bacteria can avoid therapeutics is via intracellular infection, where they hide within our own cells. Read more
 Supervisors: Dr J Burrows, Prof B Gilmore
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology
What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more
 Supervisors: Dr JF Fox, Dr JH Hodgkinson
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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MSc by Research: Glueing proteins together with small molecules

University of Dundee School of Life Sciences
Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more
 Supervisor: Prof A Ciulli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How to regulate plasticity in the brain

University of Leeds Faculty of Biological Sciences
The Kwok Lab at the School of Biomedical Science invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisor: Dr J. Kwok
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

University of Nottingham School of Medicine
Implanted medical devices are crucial in healthcare, valued at around £400 billion globally, however there is a high failure rate, often due to the foreign body reaction, where a fibrotic capsule forms around the implant with associated inflammation, loosening and infection. Read more
 Supervisors: Prof M Alexander, Prof AG Ghaemmaghami, Dr D H Kim, Prof BO Ollivere
 30 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Anticancer Phototherapeutics Based on Transition Metal Complexes

University of Sheffield Department of Chemistry
Cancer is one of the leading causes of death around the world. Although existing chemotherapy regimens are often successful in curing many common cancers, they frequently cause serious and unwanted side-effects. Read more
 Supervisor: Prof JA Thomas
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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New Anticancer Therapeutics Based on Luminescent Transition Metal Complexes

University of Sheffield Department of Chemistry
Cancer is one of the leading causes of death around the world. Over 50% of cancer tumours are treated with platinum-based metal complexes, like cisplatin and its derivatives. Read more
 Supervisor: Prof JA Thomas
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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New strategies to cryopreserve cell-based therapies

The University of Manchester Department of Chemistry
In the past decade, cell-based therapies have emerged to transform the treatment of disease, particularly cancer. Whilst potent, these therapies are challenging to deliver in practise as must be stored frozen (cryopreserved). Read more
 Supervisor: Prof m Gibson
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health
Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more
 Supervisors: Dr A Politis, Dr CP Pliotas
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry
Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more
 Supervisors: Prof E Takano, Prof H Oguri
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

University College London Department of Biochemical Engineering
Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more
 Funded PhD Programme (UK Students Only)  EPSRC Centre for Doctoral Training
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(MRC DTP CASE) Designing Peptide hydrogels as vehicles for targeted and localised in-vivo therapeutics delivery

The University of Manchester Faculty of Biology, Medicine and Health
One of the key engineering challenges in the life-science and biomedical sectors is the design and manufacturing of bespoke hydrogels for 3D cell culture, tissue engineering and cell/drug delivery. Read more
 Supervisors: Prof A Saiani, Dr K Finegan
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

The University of Manchester Department of Chemistry
Nucleotides are the building blocks of life, modulating diverse processes from protein production to cell signalling. It is therefore unsurprising that synthetic nucleoside analogues have been developed as therapeutics for the treatment of a wide range of diseases including cancers and viral infections. Read more
 Supervisors: Dr S Lovelock, Dr C Markin
 31 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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From bench to pre-clinical evaluation: a novel nucleic acid vaccine targeting tumour-associated antigens

Royal College of Surgeons in Ireland Molecular and Cellular Therapeutics
Cancer and the long-term toxicities sustained from treatment remain a public health issue for adult and paediatric patients. The spread of tumour cells is believed to account for up to 90% of cancer-related morbidities. Read more
 Supervisor: Dr O Piskareva
 1 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Breaking the resistance: alternative approaches to antibiotics discovery

Queen’s University Belfast School of Pharmacy
The World Health Organisation (WHO) identifies antimicrobial resistance (AMR) as one of the top 10 global threats to human health (http://www.who.int/). Read more
 Supervisor: Prof G Wagner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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