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Pharmaceutical / Medicinal Chemistry (clinical chemistry) PhD Projects, Programs & Scholarships

We have 8 Pharmaceutical / Medicinal Chemistry (clinical chemistry) PhD Projects, Programs & Scholarships

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We have 8 Pharmaceutical / Medicinal Chemistry (clinical chemistry) PhD Projects, Programs & Scholarships

Nutrient-Mediated Delivery of ‘Dual Warhead’ Antimicrobials

Background. Microbial resistance to antibiotics is a growing problem. Until recently, antibiotics of the fluoroquinolone-type provided some of the most active broad-spectrum antibacterial agents on the market. Read more

Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact

Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more

Novel synthetic approaches to antimicrobial natural products and investigations of their bioactivity

The aim of the project is to develop new highly effective anti-tubercular agents. Previously, it has been established that terpenes isolated from marine organisms possess a number of important antibacterial properties. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Nanotherapeutics for Improved Ocular Drug Delivery of Biologics

Eye diseases, such as age-related macular degeneration (AMD) are major causes of vision loss in the UK and worldwide. For example, approximately 600,000 people in the UK suffer from vision loss due to AMD. Read more
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