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We have 5 Pharmaceutical Chemistry (drug metabolism) PhD Projects, Programmes & Scholarships

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Pharmaceutical Chemistry (drug metabolism) PhD Projects, Programmes & Scholarships

We have 5 Pharmaceutical Chemistry (drug metabolism) PhD Projects, Programmes & Scholarships

Quantitative prediction of drug metabolism mechanism

Faculty of Pharmacy, Charles University, Department of Pharmacology and Toxicology . The project aim is the high-accuracy prediction of drug metabolism mechanism with the help of atomistic simulations at quantum accuracy and machine learning. Read more

Drug metabolism - prediction, detection, and isolation

Electrosynthesis (ES) is a green methodology for preparing and interpreting drug metabolites linked to toxicology. ES describes the synthesis of chemical compounds in an electrochemical cell. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Development of LA1011 for high affinity binding to Hsp90 for use towards healthy ageing in patients showing Alzheimer’s symptoms

  Research Group: Biochemistry
With 50 million global cases of Alzheimer’s disease (AD) and care costs of 1 trillion UK pounds (expected to triple by 2050), there is a pressing need to slow disease progression, sustain productive lives and reduce costs. Read more
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