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We have 63 Pharmaceutical Chemistry (funding) PhD Projects, Programmes & Scholarships

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Pharmaceutical Chemistry (funding) PhD Projects, Programmes & Scholarships

We have 63 Pharmaceutical Chemistry (funding) PhD Projects, Programmes & Scholarships

Development of NMR Methods for the Study of Dynamics in Solids

One fully funded PhD studentship is available in the area of nuclear magnetic resonance (NMR) of solids. The position is available for 42-months starting in October 2024. Read more

Small molecule cancer drug discovery targeting resistant disease.

Despite continuous advances in targeted cancer therapy in recent years, there remains a major challenge to combat drug resistance and poor levels of efficacy in areas of unmet medical need, such as advanced colorectal and breast cancer. Read more

Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

  Research Group: Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

Implanted medical devices are crucial in healthcare, valued at around £400 billion globally, however there is a high failure rate, often due to the foreign body reaction, where a fibrotic capsule forms around the implant with associated inflammation, loosening and infection. Read more

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia

  Research Group: Pharmacology and Experimental Therapeutics
Dementia describes a group of age-associated conditions of which cognitive decline is a major feature. Alzheimer’s disease (AD) is the most common cause of dementia and is characterised by the onset of a gradual cognitive decline. Read more

Directed Co-Crystallisation of Pharmaceuticals: developing a predictive method for co-crystallisation

  Research Group: Chemistry and Biosciences
In this project, we propose to use a combination of computational and experimental techniques to develop a predictive method for co-crystallisation. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Biological rhythms and the dopamine system in cognitive dysfunction

  Research Group: Pharmacology and Experimental Therapeutics
Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more

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