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Pharmaceutical / Medicinal Chemistry (human) PhD Projects, Programs & Scholarships

We have 28 Pharmaceutical / Medicinal Chemistry (human) PhD Projects, Programs & Scholarships

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  (BBSRC DTP CASE) Exploitation of P450 BM3 variants for production of valuable drug metabolites
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2020

Funding Type

PhD Type

The US Food and Drug Administration (FDA) have recommended that human drug metabolites (as well as their parent drugs) should be subject to testing for safety/toxicity.
  PhD Studentship Opportunity in Computational modelling of skin absorption of chemicals
  Dr T Chen, Prof G Lian
Application Deadline: 29 February 2020

Funding Type

PhD Type

Human skin is a complex organ of human body with multilayer tissues and multiple components such as sweat ducts and glands, sebaceous glands and hair follicles.
  Impact of normal and premature ageing on human macro- and microvasculature
  Research Group: Centre for Skin Sciences
  Dr K Riches-Suman, Dr M J Thornton
Applications accepted all year round

Funding Type

PhD Type

The global population is growing, with the number of births consistently higher than the number of deaths. This is because people are living for longer, due at least in part to improved lifestyle and healthcare provision.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  (BBSRC DTP) Exploring the host-microbiome interactions to promote healthy skin function
  Prof A Nicolaou, Prof A McBain, Prof C A O'Neill, Dr A Kendall
Application Deadline: 31 January 2020

Funding Type

PhD Type

The surface of our skin is an intriguing landscape covered by a diverse population of microorganisms that are collectively known as the cutaneous ‘microbiome’.
  Designing novel composite polysaccharide nanoparticles for combined diagnosis and treatment of cancers
  Dr E Barbu, Dr A Lalatsa
Applications accepted all year round

Funding Type

PhD Type

Cancer continues to impose a vast burden with regard to financial costs as well as human suffering but the progress in its treatment is hindered by the limited selectivity and significant side-effects that the current chemotherapy demonstrates, representing a major challenge for modern drug delivery.
  Molecular modelling of novel anti-cancer molecules targeting Mortalin-p53 interaction
  Dr S R Dundas, Prof A Donaldson, Prof M Jaspars
Application Deadline: 17 February 2020

Funding Type

PhD Type

Mortalin is a highly conserved member of the heat shock 70 family which, when over-expressed, plays a pivotal role in dysregulating signal pathways implicated in carcinogenesis.
  Preferential stem cell targeting using proTide nucleoside analogues
  Prof C Pepper, Dr A Pepper
Application Deadline: 14 February 2020

Funding Type

PhD Type

Applications are invited for a 3-year PhD studentship hosted at Brighton and Sussex Medical School on the University of Sussex Campus.
  Inhibiting cell metabolism to enhance tumour cell death
  Dr C Bubici, Dr S Papa
Application Deadline: 31 January 2020

Funding Type

PhD Type

As you read this, millions of your cells from your body are dying. Do not panic – this is not bad news. Most of them are either superfluous or potentially harmful, so you are better off without them.
  Comparative genomic analysis of variant features within the Neisseria spp.
  Dr L Snyder
Applications accepted all year round

Funding Type

PhD Type

The availability of rapid genome sequencing had generated an explosion of bacterial genome sequence data, much of which has not been fully explored and investigated.
  Developing effective measurement techniques for the assessment of Furan Fatty Acids levels
  Dr M Kimber
Application Deadline: 31 July 2020

Funding Type

PhD Type

The Furan Fatty Acids (FFAs) are an important class of natural products due to their nutritional health benefits and impact on inflammatory & cardiovascular…
  Reversing multidrug chemoresistance in head and neck cancer
  Dr M T Teh
Applications accepted all year round

Funding Type

PhD Type

Background. Multidrug resistance renders chemotherapeutic treatment failure in large proportion of head and neck squamous cell carcinoma (HNSCC) patients requiring multimodal therapy involving chemotherapy in conjunction with surgery and/or radiotherapy.
  Design of 3D printed microfluidic systems with engineered hydrogels for organ-on-chip applications
  Dr J Gautrot
Application Deadline: 31 January 2020

Funding Type

PhD Type

A studentship in the design of 3D printed microfluidic systems with engineered hydrogels for organ-on-chip applications is available in the group of Prof J.
  Computer Simulations of G protein-coupled Receptors
  Dr I Tikhonova
Applications accepted all year round

Funding Type

PhD Type

Many physiological processes are controlled through the activation of G protein-coupled receptors (GPCRs) by regulatory peptides, making peptide GPCRs particularly useful targets for major human diseases such as diabetes and CNS diseases.
  Peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention
  Dr G Laverty, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

HIV/AIDS is the leading cause of death in women of reproductive age worldwide. HIV and unintended pregnancies are prevalent in developing nations due to the lack of effective female contraceptive choice.
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