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Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships

We have 76 Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships

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  Chemo-enzymatic Synthesis and Potential Applications of Novel Heterocyclic Alkaloids
  Dr H Deng, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Inhibiting cell metabolism to enhance tumour cell death
  Dr C Bubici, Dr S Papa
Application Deadline: 31 January 2020

Funding Type

PhD Type

As you read this, millions of your cells from your body are dying. Do not panic – this is not bad news. Most of them are either superfluous or potentially harmful, so you are better off without them.
  Discovery of novel cancer immunotherapeutic agents
  Dr Y Mehellou
Applications accepted all year round

Funding Type

PhD Type

Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high morbidity and mortality.
  Discovery of novel treatments for Parkinson’s disease
  Dr Y Mehellou, Dr E Lane
Applications accepted all year round

Funding Type

PhD Type

Parkinson’s disease (PD) is the second most common neurological disease in the world. Current PD therapies and medical interventions are very limited and only address the symptoms of this disease highlighting the need for new and effective treatments.
  Decoding the Language of Nature: It is time for Artificial Intelligence to predict the function of natural products based on structure
  Prof R Quinn, Dr M Liu, Dr CW Wang
Applications accepted all year round

Funding Type

PhD Type

The profound and specific biological activity of natural products coupled with their immediately recognizable structures suggests a code within these structures that we are not as yet aware of.
  PhD in Continuous Manufacturing and Advanced Crystallisation

Funding Type

PhD Type

CMAC, the EPSRC Future Manufacturing Research Hub in Continuous Manufacturing and Advanced Crystallisation, is a major initiative that aims to accelerate the adoption of continuous manufacturing technologies for high value chemical products such as pharmaceuticals.
  Carbon nanotubes in the boron neutron capture therapy of cancer
  Dr G Calabrese
Applications accepted all year round

Funding Type

PhD Type

The early promise of boron neutron capture therapy as a method for the treatment of brain cancer has been mainly inhibited by the inherent toxicity associated with 10B-containing pharmacophores and the need for the ability to cross biological membranes.
  Comparative genomic analysis of variant features within the Neisseria spp.
  Dr L Snyder
Applications accepted all year round

Funding Type

PhD Type

The availability of rapid genome sequencing had generated an explosion of bacterial genome sequence data, much of which has not been fully explored and investigated.
  Investigating the chemistry of antioxidants and polysaccharides present in date-fruit (Phoenix dactylifera) as a novel/potential therapies for neoplastic and infectious diseases.
  Dr H Morgan
Applications accepted all year round

Funding Type

PhD Type

Date-fruit contains vast amount of phenols; approx. 80400µmol/100g, which portray antioxidant abilities.
  Novel Cyclic Peptides for Biomedical Imaging and Therapeutic Targeting
  Prof M Zanda
Applications accepted all year round

Funding Type

PhD Type

Cyclic Peptides have a wide range of applications as drugs and diagnostics, and have often higher receptor affinity, metabolic stability and better pharmacokinetic properties compared to their linear counterparts, but their synthesis still presents significant challenges.
  Rapid Synthesis of Fluorinated Drug Scaffolds
  Dr G Weaver
Applications accepted all year round

Funding Type

PhD Type

This project will involve the synthesis and characterisation of new heterocyclic compounds which can act as core scaffolds for drug development.
  Total synthesis of marine polycyclic ether natural products to tackle Alzheimer’s disease
  Dr M Kimber
Application Deadline: 30 September 2019

Funding Type

PhD Type

This project will develop an efficient asymmetric synthesis of marine polycyclic ether natural products.
  PhD in Continuous Manufacturing and Advanced Crystallisation

Funding Type

PhD Type

CMAC, the EPSRC Future Manufacturing Research Hub in Continuous Manufacturing and Advanced Crystallisation, is a major initiative that aims to accelerate the adoption of continuous manufacturing technologies for high value chemical products such as pharmaceuticals.
  Creating Materials to Deliver Stem Cell Products
  Dr Mark Del Borgo, Dr Ketav Kulkarni, Prof R Widdop, Prof Mibel Aguilar
Applications accepted all year round

Funding Type

PhD Type

Stem cell therapy holds immense potential as a treatment paradigm for a number of conditions. However, currently the therapeutic outcome is often limited by low cell survivability, poor integration within the host tissue of the stroke brain and non-sustained delivery over the period of treatment.
  Iontophoresis to deliver corticosteroids across buccal mucosal using hydrogel as delivery systems
  Prof M Patel, Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background. Topical delivery of drugs to treat oral mucosal disease is often challenging. This is due to, for example, the saliva washing therapeutic agents away into the gastrointestinal system, the movement of oral structures during mastication and the presence of keratinized oral mucosal surfaces.
  Computational modelling of protein dynamics in heart disease
  Dr A Fornili
Applications accepted all year round

Funding Type

PhD Type

Applications are invited from self-funded candidates interested in completing a PhD starting in October 2019 in the group of Dr Arianna Fornili (https://afornililab.wordpress.com) in the School of Biological and Chemical Sciences at Queen Mary University of London.
  Rational design of selective modulators of skeletal myosin
  Dr A Fornili, Dr J Ochala
Application Deadline: 14 October 2019

Funding Type

PhD Type

Applications are invited for a PhD studentship funded by Muscular Dystrophy UK (MDUK) starting January 2020 in Dr. Arianna Fornili’s group at Queen Mary University of London and Dr.
  Cold Plasmas for Microbial Control in the Food Chain
  Dr B Gilmore, Dr P Flynn
Application Deadline: 30 September 2019

Funding Type

PhD Type

The ability to generate plasmas (quasi-neutral, wholly or partially ionised gases) at ambient or tissue tolerable temperatures has given rise to the nascent field of plasma medicine.
  Molecular interactions in solution for multi-component crystallisation
  Dr K Edkins, Dr J Holbrey
Applications accepted all year round

Funding Type

PhD Type

Crystallisation is probably one of the most important unit operations in pharmaceutical industry for purification, as well as the generation of materials appropriate for formulation and application to the patient.
  Characterising surface properties of protein biopharmaceutical molecules
  Dr A Golovanov, Dr J Warwicker
Applications accepted all year round

Funding Type

PhD Type

Protein biologicals have great potential for the effective treatment of a wide range of diseases. However, aggregation and instability are inherent issues with all protein pharmaceuticals, which is a problem that can limit their utility and developability.
  Design, Synthesis and Biological Evaluation of novel inhibitors of the JAK-STAT signalling pathway with potential application as immune oncology agents
  Dr R Whitehead, Dr K Finegan, Prof N Turner
Applications accepted all year round

Funding Type

PhD Type

Small molecule inhibitors of the JAK-STAT signalling pathway often possess interesting biological properties with many displaying potent anti-proliferative activity towards cancer cell lines.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics
  Dr L Wong, Dr C F Blanford
Applications accepted all year round

Funding Type

PhD Type

Plastics are a broad range of solid polymeric materials that have found widespread application as industrial components and consumer goods.
  Structure based design of novel warheads for use in peptide-drug conjugates
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round

Funding Type

PhD Type

Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
  Personalised surgery for colorectal cancer cure by use of fluorescence guidance- increasing safety & cancer precision
  Dr R Cahill
Applications accepted all year round

Funding Type

PhD Type

Surgery is the best treatment for colorectal cancer, most especially for cure. It remains a major operation with considerable risks meaning that every effort should be made to ensure maximum safety and effectiveness in obtaining a complete resection.
  EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

Funding Type

PhD Type

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies.
  Magnetic hyperthemia for cancer treatment: synthesis, biofunctionalisation of nanoparticles for thermo-chemotherapy
  Prof N T K Thanh
Applications accepted all year round

Funding Type

PhD Type

Functional magnetic nanoparticles for cancer treatment. Supervisor. Prof Nguyen TK Thanh. [email protected]; http:/www.ntk-thanh.ac.uk.
  Organic electrosynthesis
  Dr J Sperry
Applications accepted all year round

Funding Type

PhD Type

The field of chemical synthesis is under constant pressure to produce molecules in a timely, economical and sustainable fashion. In this project we will demonstrate that valuable heterocyclic molecules can be efficiently synthesized in an environmentally friendly manner by simply using electric current.
  Multidisciplinary PhD Programme (3.5 years) Centre for Sustainable Chemical Technologies

Funding Type

PhD Type

Multidisciplinary PhD Programme (3.5 years). Centre for Sustainable Chemical Technologies. The Centre for Sustainable Chemical Technologies at the University of Bath is now accepting applications for the October 2019 intake.
  PhD in Continuous Manufacturing and Advanced Crystallisation

Funding Type

PhD Type

CMAC, the EPSRC Future Manufacturing Research Hub in Continuous Manufacturing and Advanced Crystallisation, is a major initiative that aims to accelerate the adoption of continuous manufacturing technologies for high value chemical products such as pharmaceuticals.
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