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Pharmaceutical / Medicinal Chemistry (january) PhD Projects, Programs & Scholarships

We have 11 Pharmaceutical / Medicinal Chemistry (january) PhD Projects, Programs & Scholarships

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  The chemical glycobiology of carbohydrate metabolism
  Prof R Field, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Carbohydrates are widespread in nature and fulfil many important biological functions. However, the biology of carbohydrates is much less well explored than that of nucleic acids and proteins.
  It’s all in the Structure: Transforming drug design by bringing together molecular simulations and machine learning
  Dr G.C. Sosso
Applications accepted all year round

Funding Type

PhD Type

The solubility of pharmaceutical drugs determines to what extent they can be absorbed. Machine learning algorithms can predict the solubility of novel drugs without the need of actually synthetizing them - thus saving substantial time and money.
  Computer Simulations of G protein-coupled Receptors
  Dr I Tikhonova
Applications accepted all year round

Funding Type

PhD Type

Many physiological processes are controlled through the activation of G protein-coupled receptors (GPCRs) by regulatory peptides, making peptide GPCRs particularly useful targets for major human diseases such as diabetes and CNS diseases.
  Enhancing intracellular delivery of antibiotics using cold atmospheric plasma
  Dr P Flynn, Prof B Gilmore
Application Deadline: 29 February 2020

Funding Type

PhD Type

Atmospheric pressure non-thermal plasma or simply cold plasmas is a partially ionized gas generated at atmospheric pressure, at temperatures suitable for treatment of heat sensitive surfaces such as skin.
  Microfabricated Engineered Systems for Sustained Ocular Drug Delivery
  Dr R Thakur, Dr D Lamprou
Applications accepted all year round

Funding Type

PhD Type

Retinal diseases that originate at the back of the eye, such as Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME), represent the leading causes of vision loss in the Western world.
  Microfluidic Synthesis of Nanomedicines for the Delivery of Biologic Drugs
  Dr D Lamprou
Applications accepted all year round

Funding Type

PhD Type

Progress in drug design has led to the development of new molecules. However, the limited ability to selectively deliver these molecules at well-defined dosing regimens remains a significant challenge.
  Peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention
  Dr G Laverty, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

HIV/AIDS is the leading cause of death in women of reproductive age worldwide. HIV and unintended pregnancies are prevalent in developing nations due to the lack of effective female contraceptive choice.
  Peptide hydrogels as novel nanotherapeutic delivery agents enhancing the anti-tumour efficacy of radiotherapy
  Dr J Coulter, Dr G Laverty
Applications accepted all year round

Funding Type

PhD Type

There is a pressing clinical need for effective localised cancer treatments. Addressing this need we will develop a novel drug delivery system comprised of a nanoparticle/drug releasing hydrogel implant.
  Responsive hydrogel platforms towards the prevention of medical device-associated infections
  Dr N Irwin, Dr C McCoy
Applications accepted all year round

Funding Type

PhD Type

Catheter-associated urinary tract infections represent a high priority global healthcare challenge. We have recently identified a suite of non-antibiotic active agents with promising antibacterial and anti-encrustation activities.
  Surface-modified silicone elastomer for medical and drug delivery devices with reduced bacterial adherence and biofilm formation
  Dr L Carson, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

All implanted medical devices, including those fabricated from silicone elastomers, are susceptible colonisation with communities of microorganisms that colonise the surface of the device and rapidly establish biofilm populations.
  USP17 as a cancer therapeutic target
  Dr J Burrows
Applications accepted all year round

Funding Type

PhD Type

USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types.
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