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Pharmaceutical / Medicinal Chemistry (surface engineering) PhD Projects, Programs & Scholarships

We have 8 Pharmaceutical / Medicinal Chemistry (surface engineering) PhD Projects, Programs & Scholarships

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  Surface-modified silicone elastomer for medical and drug delivery devices with reduced bacterial adherence and biofilm formation
  Dr L Carson, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

All implanted medical devices, including those fabricated from silicone elastomers, are susceptible colonisation with communities of microorganisms that colonise the surface of the device and rapidly establish biofilm populations.
  PhD Studentship Opportunity in Computational modelling of skin absorption of chemicals
  Dr T Chen, Prof G Lian
Application Deadline: 29 February 2020

Funding Type

PhD Type

Human skin is a complex organ of human body with multilayer tissues and multiple components such as sweat ducts and glands, sebaceous glands and hair follicles.
  Continuous Manufacturing with Carbon Nanoreactor Supported Nanoparticle Catalysts for the Self-Optimisation of Heterogenous Reduction Reactions
  Dr T Chamberlain, Dr R Bourne
Application Deadline: 28 February 2020

Funding Type

PhD Type

Project details. This industrially sponsored project, between Dr Thomas Chamberlain and Dr Richard Bourne (University of Leeds) and Dr Kevin Leslie and Dr Graeme Clemens (Process Chemistry at AstraZeneca), will enable high throughput, flow hydrogenation at scale enabling robust, continuous manufacture.
  A step change in the modelling of enzymatic catalysis
  Prof P Popelier, Dr L Johannissen
Applications accepted all year round

Funding Type

PhD Type

A deep understanding of enzymatic processes requires an atomic-level description, which is often beyond experimental techniques but achievable through synergy with computational chemistry.
  Carbon nanotubes in the boron neutron capture therapy of cancer
  Dr G Calabrese
Applications accepted all year round

Funding Type

PhD Type

The early promise of boron neutron capture therapy as a method for the treatment of brain cancer has been mainly inhibited by the inherent toxicity associated with 10B-containing pharmacophores and the need for the ability to cross biological membranes.
  Microfluidic Synthesis of Nanomedicines for the Delivery of Biologic Drugs
  Dr D Lamprou
Applications accepted all year round

Funding Type

PhD Type

Progress in drug design has led to the development of new molecules. However, the limited ability to selectively deliver these molecules at well-defined dosing regimens remains a significant challenge.
  Responsive hydrogel platforms towards the prevention of medical device-associated infections
  Dr N Irwin, Dr C McCoy
Applications accepted all year round

Funding Type

PhD Type

Catheter-associated urinary tract infections represent a high priority global healthcare challenge. We have recently identified a suite of non-antibiotic active agents with promising antibacterial and anti-encrustation activities.
  Cationic antimicrobial peptides as anticancer agents
  Dr R Green, Prof R A Frazier
Applications accepted all year round

Funding Type

PhD Type

Cationic peptides are widespread in nature where they play a key role in host defense within plants and animals. The mechanism by which these peptides interact with cell membranes potentially leads to these being less prone to antimicrobial resistance than conventional antibiotics.
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