Pharmaceutical Chemistry (structural biology) PhD Projects, Programmes & Scholarships for Self-funded Students

We have 10 Pharmaceutical Chemistry (structural biology) PhD Projects, Programmes & Scholarships for Self-funded Students

(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health

Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more

Supervisors: Dr A Politis, Dr CP Pliotas

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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MSc by Research: Glueing proteins together with small molecules

University of Dundee School of Life Sciences

Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more

Supervisor: Prof A Ciulli

Year round applications PhD Research Project Self-Funded PhD Students Only

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

University of Leeds Faculty of Biological Sciences

Research Group: Astbury Centre for Structural Molecular Biology

Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Supervisors: Prof A O'Neill, Dr M McPhillie, Prof C Fishwick

Year round applications PhD Research Project Self-Funded PhD Students Only

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Synthetic Protein-Transporters for Enhanced Transduction Activity

Queen’s University Belfast School of Pharmacy

Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more

Supervisor: Dr S Carmali

Year round applications PhD Research Project Self-Funded PhD Students Only

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Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Supervisor: Dr Muhammad Wahajuddin

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Drugs for Brain Tumours: Prodrugs of Diazopropyne

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering Virus-Like Particles for Next-Generation Vaccine Manufacturing

University of Sheffield Department of Chemical & Biological Engineering

Virus-like particles (VLPs) are structures typically composed of viral structural proteins that self-assemble into virus-like structures. Read more

Supervisors: Dr K Tee, Prof TS Wong, Dr C Evans

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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We have 10 Pharmaceutical Chemistry (structural biology) PhD Projects, Programmes & Scholarships for Self-funded Students

Pharmaceutical Chemistry (structural biology) PhD Projects, Programmes & Scholarships for Self-funded Students

We have 10 Pharmaceutical Chemistry (structural biology) PhD Projects, Programmes & Scholarships for Self-funded Students

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