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University of Reading Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships

We have 7 University of Reading Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships

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  Gene and Cell Therapy For Muscular Dystrophy, Muscular Atrophy, Diabetes and Metabolic conditions
  Dr K Foster
Applications accepted all year round
Skeletal muscle development is a complex process and a number of regulatory factors for the different steps involved in stem cell activation and proliferation through to multinucleated, post-mitotic cells have been identified.
  Robust analysis of lifetime decay of label free autofluorescence signatures from 2 photon microscopy
  Dr S Hadjiloucas, Dr J Bowen
Applications accepted all year round
The purpose of the work is to develop novel chemometric (statistical signal processing) routines. MATLAB models of lifetime will be developed in state space and system identification routines will be adopted to de-embed the associated lifetimes of the target molecules using statistically robust criteria.
  Carbohydrate analysis for biomedical applications.
  Dr S Allman
Applications accepted all year round
Changes in the patterns of carbohydrates produced by the cell can provide insights into disease states, revealing perturbations and differences in cellular metabolic processes.
  Cationic antimicrobial peptides as anticancer agents
  Dr R Green, Prof R A Frazier
Applications accepted all year round
Cationic peptides are widespread in nature where they play a key role in host defense within plants and animals. The mechanism by which these peptides interact with cell membranes potentially leads to these being less prone to antimicrobial resistance than conventional antibiotics.
  Design and synthesis of novel, targeted, anti-cancer agents
  Prof H Osborn, Dr F Greco
Applications accepted all year round
One of the major problems of cancer chemotherapy is that the drugs used have poor selectivities for cancer cells and cause damage to normal cells and organs.
  Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular diseases
  Dr S Vaiyapuri
Applications accepted all year round
Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke.
  Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers
  Dr F Greco, Prof H Osborn
Applications accepted all year round
Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier.
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