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We have 41 Pharmacology (analysis) PhD Projects, Programmes & Scholarships

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Pharmacology (analysis) PhD Projects, Programmes & Scholarships

We have 41 Pharmacology (analysis) PhD Projects, Programmes & Scholarships

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Application and development of bioinformatics and network theory methods in cardiovascular disease research and pharmacovigilance

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy
To be able to discover novel drug targets we aim to develop software based on network theoretic approaches that are capable to identify mediators and pathways involved in the pathomechanism of various cardiovascular diseases by the analysis of datasets assessed with high throughput molecular biological techniques (e.g. Read more
 Supervisor: Dr B Ágg
 Year round applications  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

University of Liverpool Department of Pharmacology and Therapeutics
Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more
 Supervisors: Dr M Cross, Prof C Goldring
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Integrated omics approach to psychiatric disorders

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
In psychiatry, the selection of antipsychotics and antidepressants is led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). Read more
 Supervisors: Prof K Poterlowicz, Dr S McLean
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Inflammatory Arthritis in Childhood: Impact, Outcomes and Safety of Treatment

The University of Manchester Faculty of Biology, Medicine and Health
Juvenile Idiopathic Arthritis is the most common inflammatory arthritis of childhood. Although less common than arthritis in adults, a diagnosis of arthritis in a child can have lasting impacts on that child and their families through their entire lifespan. Read more
 Supervisors: Prof K Hyrich, Dr L Kearsley-Fleet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Analysing the role of statins in cardiovascular protection

University of Liverpool Department of Pharmacology and Therapeutics
Drug-induced cardiovascular toxicity is a major problem affecting a number of cancer chemotherapy drugs (Cross et al., 2015). Read more
 Supervisors: Dr M Cross, Dr B Wilm, Dr AM Mondru
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Queen’s University Belfast School of Pharmacy
Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more
 Supervisors: Dr I Tikhonova, Dr B Plouffe
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Transcriptome biomarkers and mechanisms of chemoresistance

Queen Mary University of London Institute of Dentistry
Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more
 Supervisor: Dr M T Teh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The use of Drosophila melanogaster to identify novel therapeutic agents for Alzheimer’s disease

University of Nottingham School of Life Sciences
Since 2003, our understanding of the causes of Alzheimer’s disease (AD) have improved considerably, however, in that time only one new drug treatment has been approved. Read more
 Supervisors: Dr M Georgiou, Dr Z Zhu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

University of Reading Department of Biomedical Sciences
Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more
 Supervisor: Dr S Boateng
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
 Supervisor: Prof T Gaunt
 20 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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MScR - Advancing novel methods of assessing apathy-related behaviour in rodents

University of Bristol School of Physiology, Pharmacology & Neuroscience
Apathy is a multidimensional syndrome consisting of behavioural, emotional and cognitive components that ultimately lead to a loss of motivation to engage with daily life. Read more
 Supervisors: Prof E S J Robinson, Dr M Jackson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Vascularisation of tumour organoids for mechanistic and drug development

University of Dundee School of Medicine
Gliomas such as are the most common form of brain tumour, a subset Glioblastoma (GBM) are devastating adult brain cancer with high rates of recurrence and treatment resistance. Read more
 Supervisors: Dr C Murdoch, Dr S Banerjee
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Preformulation study of RARγ and VDR hybrid compounds

Medical University of Vienna Institute for Pathophysiologie and Allergy
The doctoral candidate (DC) will perform preformulation characterisation and development of formulation prototypes at Trinity College Dublin (TCD), Ireland. Read more
 Supervisor: Assoc Prof LT Tajber
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics
Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more
 Supervisor: Dr RB Burton
 1 July 2024  PhD Research Project  Self-Funded PhD Students Only
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